Evidence map›Paper›PMID 33372201›Full record

ArticleNeurosurgery2021

Neuromodulation for Chronic Pelvic Pain: A Single-Institution Experience With a Collaborative Team.

Cheyanne Bridger, Tarun Prabhala, Rachael Dawson, Olga Khazen, Jacquelyn MacDonell, Marisa DiMarzio, Michael D Staudt, Elise J B De, Charles Argoff, Julie G Pilitsis

Open access · greenAbstract read
In one paragraph

Article in Neurosurgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
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  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Cheyanne BridgerDepartment of Neurosurgery, Albany Medical College, Albany, New York.
Tarun PrabhalaDepartment of Neuroscience and Experimental Therapeutics, Albany Medical College, Albany, New York.
Rachael DawsonDepartment of Neuroscience and Experimental Therapeutics, Albany Medical College, Albany, New York.
Olga KhazenDepartment of Neuroscience and Experimental Therapeutics, Albany Medical College, Albany, New York.
Jacquelyn MacDonellDepartment of Neuroscience and Experimental Therapeutics, Albany Medical College, Albany, New York.
Marisa DiMarzioDepartment of Neuroscience and Experimental Therapeutics, Albany Medical College, Albany, New York.
Michael D StaudtDepartment of Neurosurgery, Albany Medical College, Albany, New York.
Elise J B DeDepartment of Urology, Massachusetts General Hospital, Boston, Massachusetts.
Charles ArgoffDepartment of Neurology, Albany Medical College, Albany, New York.
Julie G PilitsisDepartment of Neurosurgery, Albany Medical College, Albany, New York.
Albany Medical Center Hospital · USMassachusetts General Hospital · US

Funding

High-Resolution, Spinal Cord Stimulation for Non-Opioid Treatment of Neuropathic PainU44NS115111 · NINDS · MICRO-LEADS, INC. · PI MCLAUGHLIN, BRYAN L · 2019 to 2025
$9.8M
MR-Guided Precision Conformal Ablation Therapy for Brain TumorsR01CA166379 · NCI · WORCESTER POLYTECHNIC INSTITUTE · PI FISCHER, GREGORY S, PILITSIS, JULIE GEORGIA · 2013 to 2022
$6.5M
NCI NIH HHS R01 CA166379NINDS NIH HHS U44 NS115111
6 · The paper itself

Abstract

backgroundSecondary to the complex care, involved specialty providers, and various etiologies, chronic pelvic pain patients do not receive holistic care.

objectiveTo compare our general and neuromodulation cohorts based on referrals, diagnosis, and therapy and describe our neuromodulation patients.

methodsA multidisciplinary team was established at our center. The intake coordinator assessed demographics and facilitated care of enrolled patients. Outcomes were compared using minimal clinical important difference of current Numerical Rating Scale (NRS) between patients with neuropathic pain who received neuromodulation and those who did not. The neuromodulation cohort completed outcome metrics at baseline and recent follow-up, including NRS score (best, worst, and current), Oswestry Disability Index (ODI), Beck Depression Inventory, and Pain Catastrophizing Scale.

resultsOver 7 yr, 233 patients were referred to our consortium and 153 were enrolled. A total of 55 patients had neuropathic pain and 44 of those were managed medically. Eleven underwent neuromodulation. A total of 45.5% patients of the neuromodulation cohort were classified as responders by minimal clinically important difference compared to 26.6% responders in the control cohort at most recent follow-up (median 25 and 33 mo, respectively). Outcome measures revealed improvement in NRS at worst (P = .007) and best (P = .025), ODI (P = .014), and Pain Catastrophizing Scale Rumination (P = .043).

conclusionEleven percent of patients were offered neuromodulation. There were more responders in the neuromodulation cohort than the conservatively managed neuropathic pain cohort. Neuromodulation patients showed significant improvement at 29 mo in NRS best and worst pain, disability, and rumination. We share our algorithm for patient management.

Indexed as

Patient Care TeamAdultAgedAged, 80 and overChronic PainCohort StudiesFemaleFollow-Up StudiesHumansMaleMiddle AgedNeuralgiaPain MeasurementPelvic PainSurveys and QuestionnairesTranscutaneous Electric Nerve StimulationChronic painDorsal root ganglion stimulationIntrathecal pain pumpNeuromodulationPelvic pain

Identifiers

PMID33372201
PMCPMC7956019
OpenAlexW3115972719

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.