Evidence map›Paper›PMID 33372143›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

Cryoelectron microscopy structure and mechanism of the membrane-associated electron-bifurcating flavoprotein Fix/EtfABCX.

Xiang Feng, Gerrit J Schut, Gina L Lipscomb, Huilin Li, Michael W W Adams

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 33 citations in OpenAlex.

  1. Biophysical journal · 2026
    Article
  2. Article
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  4. From single step hops to emergent biological phenomena.Journal of inorganic biochemistry · 2026
    Review
  5. An electron-bifurcating "plug" to a protein nanowire in tungsten-dependent aldehyde detoxification.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
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  10. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Xiang FengDepartment of Structural Biology, Van Andel Institute, Grand Rapids, MI 49503.ORCID 0000-0002-4441-3152
Gerrit J SchutDepartment of Biochemistry and Molecular Biology, University of Georgia, Athens, GA 30602.ORCID 0000-0002-3694-1799
Gina L LipscombDepartment of Biochemistry and Molecular Biology, University of Georgia, Athens, GA 30602.
Huilin LiDepartment of Structural Biology, Van Andel Institute, Grand Rapids, MI 49503 huilin.li@vai.org adams@bmb.uga.edu.ORCID 0000-0001-8085-8928
Michael W W AdamsDepartment of Biochemistry and Molecular Biology, University of Georgia, Athens, GA 30602 huilin.li@vai.org adams@bmb.uga.edu.ORCID 0000-0002-9796-5014
University of Georgia · USVan Andel Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The electron-transferring flavoprotein-menaquinone oxidoreductase ABCX (EtfABCX), also known as FixABCX for its role in nitrogen-fixing organisms, is a member of a family of electron-transferring flavoproteins that catalyze electron bifurcation. EtfABCX enables endergonic reduction of ferredoxin (

Indexed as

Bacterial ProteinsCatalysisCryoelectron MicroscopyElectronsElectron-Transferring FlavoproteinsElectron TransportFerredoxinsFlavinsFlavoproteinsIron-Sulfur ProteinsModels, MolecularNADNitrogen FixationOxidation-ReductionPyrococcus furiosusQuinone ReductasesBacterial ProteinsElectron-Transferring FlavoproteinsFerredoxinsFlavinsFlavoproteinsIron-Sulfur ProteinsNADQuinone ReductasesVitamin K 2electron bifurcationflaviniron-sulfur clustermenaquinoneThermotoga

Identifiers

PMID33372143
PMCPMC7812768
OpenAlexW3113857526

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.