Evidence map›Paper›PMID 33372068›Full record

ArticleBMJ open2020

Risk factors for mental illness in adults with atopic eczema or psoriasis: protocol for a systematic review.

Elizabeth I Adesanya, Yochai Schonmann, Joseph F Hayes, Rohini Mathur, Amy R Mulick, Lauren Rayner, Liam Smeeth, Catherine H Smith, Sinéad M Langan, Kathryn E Mansfield

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Elizabeth I AdesanyaDepartment of Non-Communicable Disease Epidemiology, London School of Hygiene & Tropical Medicine, London, UK elizabeth.adesanya@lshtm.ac.uk.ORCID 0000-0002-8912-7520
Yochai SchonmannSiaal Research Center for Family Medicine and Primary Care, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel.
Joseph F HayesDivision of Psychiatry, University College London, London, UK.
Rohini MathurDepartment of Non-Communicable Disease Epidemiology, London School of Hygiene & Tropical Medicine, London, UK.ORCID 0000-0002-3817-8790
Amy R MulickDepartment of Non-Communicable Disease Epidemiology, London School of Hygiene & Tropical Medicine, London, UK.ORCID 0000-0002-4009-2080
Lauren RaynerDepartment of Psychological Medicine, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, London, UK.
Liam SmeethDepartment of Non-Communicable Disease Epidemiology, London School of Hygiene & Tropical Medicine, London, UK.
Catherine H SmithSt John's Institute of Dermatology, Guys and St Thomas' Foundation Trust and King's College London, London, UK.
Sinéad M LanganDepartment of Non-Communicable Disease Epidemiology, London School of Hygiene & Tropical Medicine, London, UK.ORCID 0000-0002-7022-7441
Kathryn E MansfieldDepartment of Non-Communicable Disease Epidemiology, London School of Hygiene & Tropical Medicine, London, UK.ORCID 0000-0002-2551-410X
London School of Hygiene & Tropical Medicine · GBKing's College London · GBBen-Gurion University of the Negev · ILUniversity College London · GB

Funding

Department of Health PB-PG-0418-20025Wellcome TrustWellcome Trust 205039/Z/16/Z
6 · The paper itself

Abstract

introductionEvidence indicates that people with the common inflammatory skin diseases atopic eczema or psoriasis are at increased risk of mental illness. However, the reasons for the relationship between skin disease and common mental disorders (ie, depression and anxiety) or severe mental illnesses (ie, schizophrenia, bipolar disorder and other psychoses) are unclear. Therefore, we aim to synthesise the available evidence regarding the risk factors for mental illness in adults with atopic eczema or psoriasis. METHODS AND ANALYSIS: We will conduct a systematic review of randomised controlled trials, cohort, case-control and cross-sectional studies. We will search the following databases from inception to March 2020: Medline, Embase, Global Health, Scopus, the Cochrane Library, Web of Science, Base, PsycInfo, the Global Resource of Eczema Trials, and the grey literature databases Open Grey, PsycExtra and the New York Academy of Medicine Grey Literature Report. We will also search the bibliographies of eligible studies and relevant systematic reviews to identify additional relevant studies. Citation searching of large summary papers will be used to further identify relevant publications. Two reviewers will initially review study titles and abstracts for eligibility, followed by full text screening. We will extract data using a standardised data extraction form. We will assess the risk of bias of included studies using the Quality in Prognosis Studies tool. We will synthesise data narratively, and if studies are sufficiently homogenous, we will consider a meta-analysis. We will assess the quality of the evidence using the Grading of Recommendations, Assessment, Development and Evaluation framework. ETHICS AND DISSEMINATION: Ethical approval is not required for a systematic review. Results of the review will be published in a peer-reviewed journal and disseminated through conferences. PROSPERO REGISTRATION NUMBER: CRD42020163941.

Indexed as

Dermatitis, AtopicMental DisordersPsoriasisAdultCross-Sectional StudiesHumansMeta-Analysis as TopicNew YorkRisk FactorsSystematic Reviews as Topicanxiety disordersdepression & mood disorderseczemamental healthpsoriasisschizophrenia & psychotic disorders

Identifiers

PMID33372068
PMCPMC7772326
OpenAlexW3113648436

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.