Evidence map›Paper›PMID 33372015›Full record

ArticleBMJ case reports2020

Cardiac tamponade from anticoagulant-related spontaneous haemopericardium in a patient with ischaemic cardiomyopathy and heart failure.

Alicia Lefas, Neil Bodagh, Jiliu Pan, Ali Vazir

Open access · greenAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Alicia LefasCardiology Department, Royal Brompton and Harefield NHS Foundation Trust, London, UK.
Neil BodaghCardiology Department, Royal Brompton and Harefield NHS Foundation Trust, London, UK neil.bodagh@nhs.net.ORCID http://orcid.org/0000-0001-5475-5298
Jiliu PanCardiology Department, Royal Brompton and Harefield NHS Foundation Trust, London, UK.ORCID http://orcid.org/0000-0001-7435-1901
Ali VazirCardiology Department, Royal Brompton and Harefield NHS Foundation Trust, London, UK.
Royal Brompton & Harefield NHS Foundation Trust · GBChelsea and Westminster Hospital NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We describe the case of an 86-year-old man with a background of severe left ventricular dysfunction and ischaemic cardiomyopathy who, having been optimised for heart failure therapy in hospital, unexpectedly deteriorated again with hypotension and progressive renal failure over the course of 2 days. Common causes of decompensation were ruled out and a bedside echocardiogram unexpectedly diagnosed new pericardial effusion with tamponade physiology. The patient underwent urgent pericardiocentesis and 890 mL of haemorrhagic fluid was drained. Common causes for haemopericardium were ruled out, and the spontaneous haemopericardium was thought to be related to introduction of rivaroxaban anticoagulation. The patient made a full recovery and was well 2 months following discharge. This case highlights the challenges of diagnosing cardiac tamponade in the presence of more common disorders that share similar non-specific clinical features. In addition, this case adds to growing evidence that therapy with direct oral anticoagulants can be complicated by spontaneous haemopericardium, especially when coadministered with other agents that affect clotting, renal dysfunction and cytochrome P3A5 inhibitors.

Indexed as

Acute Kidney InjuryAged, 80 and overAnticoagulantsCardiac TamponadeCytochrome P-450 CYP3A InhibitorsDiagnosis, DifferentialDrainageEchocardiographyHeart FailureHumansHypotensionMaleMyocardial IschemiaPericardial EffusionRivaroxabanVentricular Dysfunction, LeftAnticoagulantsCytochrome P-450 CYP3A InhibitorsRivaroxabanhaematology (drugs and medicines)heart failurepericardial disease

Identifiers

PMID33372015
PMCPMC7772303
OpenAlexW3115271807

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.