ArticleHematology, transfusion and cell therapy
Sickle cell disease related mortality in Brazil, 2000-2018.
Article in Hematology, transfusion and cell therapy. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 33 citations in OpenAlex.
- Risk of vaso-occlusive crisis requiring hospitalization in sickle cell disease patients in brazil: retrospective cohort study of real-world data.Annals of hematology · 2026Article
- Alendronate preserves bone mineral density in adults with sickle cell disease and osteoporosis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025Article
- Epidemiological profile trends and cost of sickle cell disease in Brazil from 2008 to 2022.Acta cirurgica brasileira · 2025Article
- Sickle cell disease and increased adverse maternal and perinatal outcomes in different genotypes.Hematology, transfusion and cell therapy · 2024Article
- Multi-center study on mortality in children, and adults with sickle cell anemia-risk factors and causes of death.Scientific reports · 2024Article
- Mortality trends and sociodemographic factors associated with early death in sickle cell disease patients in the state of São Paulo.Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo · 2024Article
- Transfusion of packed red blood cells in adults with sickle cell anemia treated at an emergency hospital.Revista da Associacao Medica Brasileira (1992) · 2024Article
- Mortality related to sickle cell disease and COVID-19 in Brazil, 2020.Revista da Associacao Medica Brasileira (1992) · 2024Article
- Covid-19 impacts: Ethnic and regional inequalities in sickle cell disease patient care in Brazil.Heliyon · 2023Article
- Main Complications during Pregnancy and Recommendations for Adequate Antenatal Care in Sickle Cell Disease: A Literature Review.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2022Review
- Cost analysis of acute care resource utilization among individuals with sickle cell disease in a middle-income country.BMC health services research · 2022Article
- Maternal mortality among women with sickle cell disease in Jamaica over two decades (1998-2017).EClinicalMedicine · 2022Article
- Clinical-Epidemiological Characteristics and Mortality in Patients with Sickle Cell Anemia: A Retrospective Cohort Study of 1980 at 2018.International journal of general medicine · 2022Article
- Economic burden of sickle cell disease in Brazil.PloS one · 2022Article
- Mortality attributed to sickle cell disease in children and adolescents in Brazil, 2000-2019.Revista de saude publica · 2022Article
- Epidemiological profile trends and cost of pediatric sickle cell disease in Brazil from 2008 to 2022.Jornal de pediatriaArticle
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThere is a demand to update national mortality trends data related to sickle cell disease (SCD) in Brazil. This study describes causes of death and mortality issues related to SCD using the multiple-cause-of-death methodology.
methodsThe annual SCD mortality data was extracted from the public databases of the Mortality Information System by researching deaths in rubric D57 "sickle-cell disorders" of the International Classification of Diseases, Tenth Revision and processed by the Multiple Cause Tabulator.
resultsFrom 2000 to 2018 in Brazil, a total of 9817 deaths related to SCD occurred during the 19-year period, as the underlying cause in 6924 (70.5%) and as the associated cause of death in 2893 (29.5%). The mean and median ages at death during the entire period were significantly lower for males, 29.4 (±19.6) and 27.5 (15.5-41.5), respectively, than for females, 33.3 (±20.3) and 31.0 (19.5-46.5), respectively. The leading SCD overall associated causes of death were septicemias (32.1%), followed by pneumonias (19.4%) and respiratory failure (18.2%). On certificates with SCD as an associated cause, the underlying causes of death were circulatory system diseases (8.7%), followed, in males, by digestive system and infectious diseases and respiratory system failures, while in females, maternal deaths, included in the chapter on pregnancy, childbirth and the puerperium, accounting for 4.6% of female deaths, were succeeded by digestive system and infectious diseases.
conclusionThis study revised mortality data on death rate trends, underlying and associated causes of death, age at death and regional distribution of death in Brazil.
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