Evidence map›Paper›PMID 33371901›Full record

ReviewBiology direct2020

The immune system view of the coronavirus SARS-CoV-2.

Ivana Celardo, Luigia Pace, Loredana Cifaldi, Carlo Gaudio, Vincenzo Barnaba

Open access · goldAbstract readReview
In one paragraph

Review in Biology direct, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Ivana CelardoDipartimento di Scienze Cliniche Internistiche, Anestesiologiche e Cardiovascolari, Sapienza Università di Roma, Rome, Italy.
Luigia PaceArmenise-Harvard Immune Regulation Unit, Italian Institute for Genomic Medicine, FPO IRCCS Candiolo, Turin, Italy.
Loredana CifaldiAcademic Department of Pediatrics (DPUO),, Ospedale Pediatrico Bambino Gesù,, IRCCS, Rome,, 00165, Italy.
Carlo GaudioDipartimento di Scienze Cliniche Internistiche, Anestesiologiche e Cardiovascolari, Sapienza Università di Roma, Rome, Italy.
Vincenzo BarnabaDipartimento di Scienze Cliniche Internistiche, Anestesiologiche e Cardiovascolari, Sapienza Università di Roma, Rome, Italy. vincenzo.barnaba@uniroma1.it.
Sapienza University of Rome · ITBambino Gesù Children's Hospital · ITItalian institute for Genomic Medicine · IT

Funding

Cancer Research UK 26813Fondazione Italiana per la Ricerca sul Cancro IG]-2014-17 id. 15199 - IG-2017-22 id. 19939Fondazione Italiana Sclerosi Multipla 2015/R/04International Network Institut Pasteur PTR n. 20-16Ministero della Salute RF-2010-2310438 and RF 2010-2318269The Accelerated Award 2018 Id.22794
6 · The paper itself

Abstract

Knowing the "point of view" of the immune system is essential to understand the characteristic of a pandemic, such as that generated by the Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV)-2, responsible for the Coronavirus Disease (COVID)-19. In this review, we will discuss the general host/pathogen interactions dictating protective immune response or immunopathology, addressing the role of immunity or immunopathology in influencing the clinical infection outcome, and debate the potential immunoprophylactic and immunotherapy strategies required to fight the virus infection.

Indexed as

AnimalsAntibodies, MonoclonalAutoimmunityCOVID-19COVID-19 VaccinesHost-Pathogen InteractionsHumansImmune EvasionImmune SystemImmunityImmunity, InnateImmunotherapyAntibodies, MonoclonalCOVID-19 VaccinesCoronavirusCOVID-19Monoclonal antibodiesSARS-CoV-2Vaccine

Identifiers

PMID33371901
PMCPMC7769684
OpenAlexW3108938373

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.