Evidence map›Paper›PMID 33371460›Full record

ArticleViruses2020

Live Attenuated African Swine Fever Viruses as Ideal Tools to Dissect the Mechanisms Involved in Cross-Protection.

Elisabeth Lopez, Juanita van Heerden, Laia Bosch-Camós, Francesc Accensi, Maria Jesus Navas, Paula López-Monteagudo, Jordi Argilaguet, Carmina Gallardo, Sonia Pina-Pedrero, Maria Luisa Salas and 2 more

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
8.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 49 citations in OpenAlex.

  1. Article
  2. Hybrid genotype I and II ASFVEmerging microbes & infections · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Seroimmunotyping of African swine fever virus.Frontiers in microbiology · 2023
    Article
  14. Vaccines for African swine fever: an update.Frontiers in microbiology · 2023
    Review
  15. Article
  16. Review
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 3 countries.

Elisabeth LopezIRTA, Centre de Recerca en Sanitat Animal (IRTA-CReSA), Campus de la Universitat Autonoma de Barcelona, 08193 Bellaterra, Spain.ORCID 0000-0003-4253-330X
Juanita van HeerdenAgricultural Research Council-Onderstepoort Veterinary Research, Pretoria 0110, South Africa.ORCID 0000-0002-3048-315X
Laia Bosch-CamósIRTA, Centre de Recerca en Sanitat Animal (IRTA-CReSA), Campus de la Universitat Autonoma de Barcelona, 08193 Bellaterra, Spain.
Francesc AccensiIRTA, Centre de Recerca en Sanitat Animal (IRTA-CReSA), Campus de la Universitat Autonoma de Barcelona, 08193 Bellaterra, Spain.
Maria Jesus NavasIRTA, Centre de Recerca en Sanitat Animal (IRTA-CReSA), Campus de la Universitat Autonoma de Barcelona, 08193 Bellaterra, Spain.
Paula López-MonteagudoIRTA, Centre de Recerca en Sanitat Animal (IRTA-CReSA), Campus de la Universitat Autonoma de Barcelona, 08193 Bellaterra, Spain.
Jordi ArgilaguetIRTA, Centre de Recerca en Sanitat Animal (IRTA-CReSA), Campus de la Universitat Autonoma de Barcelona, 08193 Bellaterra, Spain.ORCID 0000-0001-5924-2774
Carmina GallardoCentro de Investigación en Sanidad Animal (CISA-INIA), 28130 Madrid, Spain.
Sonia Pina-PedreroIRTA, Centre de Recerca en Sanitat Animal (IRTA-CReSA), Campus de la Universitat Autonoma de Barcelona, 08193 Bellaterra, Spain.
Maria Luisa SalasCentro de Biología Molecular Severo Ochoa, Consejo Superior de Investigaciones Científicas and Universidad Autònoma de Madrid, 28049 Madrid, Spain.
Jeremy SaltGALVmed, Doherty Building, Pentlands Science Park, Bush Loan, Penicuik Edinburgh EH26 0PZ, UK.ORCID 0000-0003-0404-6535
Fernando RodriguezIRTA, Centre de Recerca en Sanitat Animal (IRTA-CReSA), Campus de la Universitat Autonoma de Barcelona, 08193 Bellaterra, Spain.ORCID 0000-0001-7361-8408
Universitat Autònoma de Barcelona · ESCentro de Investigación en Sanidad AnimalConsejo Superior de Investigaciones Científicas · ESGlobal Alliance for Livestock Veterinary Medicines · GBOnderstepoort Veterinary Institute · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

African swine fever (ASF) has become the major threat for the global swine industry. Furthermore, the epidemiological situation of African swine fever virus (ASFV) in some endemic regions of Sub-Saharan Africa is worse than ever, with multiple virus strains and genotypes currently circulating in a given area. Despite the recent advances on ASF vaccine development, there are no commercial vaccines yet, and most of the promising vaccine prototypes available today have been specifically designed to fight the genotype II strains currently circulating in Europe, Asia, and Oceania. Previous results from our laboratory have demonstrated the ability of BA71∆CD2, a recombinant LAV lacking CD2v, to confer protection against homologous (BA71) and heterologous genotype I (E75) and genotype II (Georgia2007/01) ASFV strains, both belonging to same clade (clade C). Here, we extend these results using BA71∆CD2 as a tool trying to understand ASFV cross-protection, using phylogenetically distant ASFV strains. We first observed that five out of six (83.3%) of the pigs immunized once with 10

Indexed as

African Swine FeverAfrican Swine Fever VirusAnimalsAntibodies, ViralAntibody SpecificityCell LineChlorocebus aethiopsCOS CellsCross ProtectionGenotypeImmunizationImmunoglobulin GSwineVaccines, AttenuatedViral ProteinsViral VaccinesAntibodies, ViralImmunoglobulin GVaccines, AttenuatedViral ProteinsViral VaccinesAfrican swine fever viruscross-protectionlive attenuate vaccine

Identifiers

PMID33371460
PMCPMC7767464
OpenAlexW3114021938

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.