Evidence map›Paper›PMID 33371284›Full record

ReviewMolecules (Basel, Switzerland)2020

Fluorine-18-Labeled Fluorescent Dyes for Dual-Mode Molecular Imaging.

Maxime Munch, Benjamin H Rotstein, Gilles Ulrich

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

  1. Biodistribution, Safety Profile, and Radiation Dosimetry of [Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025
    Article
  2. Review
  3. Article
  4. Article
  5. ClickablePharmaceuticals (Basel, Switzerland) · 2022
    Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Maxime MunchUniversity of Ottawa Heart Institute, Ottawa, ON K1Y 4W7, Canada.
Benjamin H RotsteinUniversity of Ottawa Heart Institute, Ottawa, ON K1Y 4W7, Canada.ORCID 0000-0001-9707-9357
Gilles UlrichInstitut de Chimie et Procédés pour l'Énergie, l'Environnement et la Santé (ICPEES), UMR CNRS 7515, École Européenne de Chimie, Polymères et Matériaux (ECPM), 25 rue Becquerel, CEDEX 02, 67087 Strasbourg, France.ORCID 0000-0002-6980-6091
University of Ottawa · CACentre National de la Recherche Scientifique · FR

Funding

CIHR 366633Ontario Ministry of Research, Innovation and Science ER17-13-119
6 · The paper itself

Abstract

Recent progress realized in the development of optical imaging (OPI) probes and devices has made this technique more and more affordable for imaging studies and fluorescence-guided surgery procedures. However, this imaging modality still suffers from a low depth of penetration, thus limiting its use to shallow tissues or endoscopy-based procedures. In contrast, positron emission tomography (PET) presents a high depth of penetration and the resulting signal is less attenuated, allowing for imaging in-depth tissues. Thus, association of these imaging techniques has the potential to push back the limits of each single modality. Recently, several research groups have been involved in the development of radiolabeled fluorophores with the aim of affording dual-mode PET/OPI probes used in preclinical imaging studies of diverse pathological conditions such as cancer, Alzheimer's disease, or cardiovascular diseases. Among all the available PET-active radionuclides,

Indexed as

AnimalsDiseaseFluorescenceFluorescent DyesFluorine RadioisotopesHumansMolecular ImagingNeoplasmsOptical ImagingPositron-Emission TomographyRadiopharmaceuticalsFluorescent DyesFluorine-18Fluorine RadioisotopesRadiopharmaceuticalsdual-mode imagingfluorescenceFluorine-18molecular imagingpositron emission tomographyradiofluorination

Identifiers

PMID33371284
PMCPMC7766373
OpenAlexW3115695685

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.