Evidence map›Paper›PMID 33371256›Full record

ArticlePharmaceuticals (Basel, Switzerland)2020

Imidazole and Imidazolium Antibacterial Drugs Derived from Amino Acids.

Adriana Valls, Jose J Andreu, Eva Falomir, Santiago V Luis, Elena Atrián-Blasco, Scott G Mitchell, Belén Altava

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Special Issue "Novel Antibacterial Agents".Pharmaceuticals (Basel, Switzerland) · 2021
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Adriana VallsDepartamento de Química Inorgánica y Orgánica, Universitat Jaume I, Av. Sos Baynat s/n, 12071 Castellón, Spain.ORCID 0000-0002-5011-4706
Jose J AndreuDepartamento de Química Inorgánica y Orgánica, Universitat Jaume I, Av. Sos Baynat s/n, 12071 Castellón, Spain.
Eva FalomirDepartamento de Química Inorgánica y Orgánica, Universitat Jaume I, Av. Sos Baynat s/n, 12071 Castellón, Spain.ORCID 0000-0003-0329-6313
Santiago V LuisDepartamento de Química Inorgánica y Orgánica, Universitat Jaume I, Av. Sos Baynat s/n, 12071 Castellón, Spain.ORCID 0000-0002-8159-3447
Elena Atrián-BlascoInstituto de Nanociencia y Materiales de Aragón (INMA), Consejo Superior de Investigaciones Científicas-Universidad de Zaragoza, 50009 Zaragoza, Spain.ORCID 0000-0002-3830-7847
Scott G MitchellInstituto de Nanociencia y Materiales de Aragón (INMA), Consejo Superior de Investigaciones Científicas-Universidad de Zaragoza, 50009 Zaragoza, Spain.ORCID 0000-0003-4848-414X
Belén AltavaDepartamento de Química Inorgánica y Orgánica, Universitat Jaume I, Av. Sos Baynat s/n, 12071 Castellón, Spain.
Universitat Jaume I · ESConsejo Superior de Investigaciones Científicas · ES

Funding

H2020 Marie Skłodowska-Curie Actions 845427Ministerio de Ciencia e Innovación FPU15/01191Ministerio de Ciencia e Innovación PID2019-109333RB-I00Ministerio de Ciencia e Innovación RTI2018-098233-B-C22Pla de Promoció de la Investigació de la Universitat Jaume I UJI-B2019-40
6 · The paper itself

Abstract

The antibacterial activity of imidazole and imidazolium salts is highly dependent upon their lipophilicity, which can be tuned through the introduction of different hydrophobic substituents on the nitrogen atoms of the imidazole or imidazolium ring of the molecule. Taking this into consideration, we have synthesized and characterized a series of imidazole and imidazolium salts derived from

Indexed as

aggregationamino acidantibacterial agentsimidazole and imidazolium saltslipophilicity

Identifiers

PMID33371256
PMCPMC7767166
OpenAlexW3118046645

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.