Evidence map›Paper›PMID 33371227›Full record

SynthesisInternational journal of environmental research and public health2020

The Microbial Quality and Safety of Blenderised Enteral Nutrition Formula: A Systematic Review.

Omorogieva Ojo, Amanda Rodrigues Amorim Adegboye, Osarhumwese Osaretin Ojo, Xiaohua Wang, Joanne Brooke

Abstract readSystematic Review
In one paragraph

Synthesis in International journal of environmental research and public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. The effect of blended tube feeding compared to conventional formula on clinical outcomes in adults: A systematic review.Nutrition & dietetics : the journal of the Dietitians Association of Australia · 2026
    Pooled it
  2. Trial
  3. Review
  4. Observational
  5. Article
  6. Article
  7. Enteral feeding barriers in the intensive care unit of a tertiary hospital in Ghana.The Southern African journal of critical care : the official journal of the Critical Care Society · 2026
    Article
  8. Nutrition Support Interventions for Children and Young People Treated for Osteosarcoma: A Scoping Review.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2025
    Article
  9. Homemade formulas for nutrition support in chronic kidney disease: A narrative review of the opportunity for education, research, and innovation.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2025
    Review
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Omorogieva OjoFaculty of Education, Health and Human Sciences, School of Health Sciences, University of Greenwich, Avery Hill Campus, Avery Hill Road, London SE9 2UG, UK.ORCID 0000-0003-0071-3652
Amanda Rodrigues Amorim AdegboyeFaculty of Health and Life Sciences, School of Nursing, Midwifery and Health, Coventry University Priory Street, Coventry CV1 5FB, UK.ORCID 0000-0003-2780-0350
Osarhumwese Osaretin OjoSouth London and Maudsley NHS Foundation Trust, University Hospital, Lewisham High Street, London SE13 6LH, UK.
Xiaohua WangThe School of Nursing, Soochow University, Suzhou 215006, China.
Joanne BrookeFaculty of Health, Education and Life Sciences, Ravensbury House, Birmingham City University, City South Campus, Birmingham B15 3TN, UK.ORCID 0000-0003-0325-2142

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The use of blenderised enteral nutrition formula (ENF) is on the increase globally. However, concerns remain regarding the microbial quality and safety of blenderised ENF compared with standard recommendations and commercial ENF.

aimThis was a systematic review which sought to compare the microbial quality of blenderised ENF and commercial ENF and to evaluate the effect of storage time on blenderised ENF.

methodFour databases (Pubmed, EMBASE, PSYCInfo and Google scholar) were searched for relevant articles based on the Population, Intervention, Comparator, Outcomes framework.

resultsEleven studies which met the criteria were included in the systematic review. Two major areas were identified; Microbial Quality of Blenderised ENF versus Commercial ENF; and The Effect of Storage Time on Microbial Quality of Blenderised ENF. Overall, 72.7% of the studies showed microbial contamination in blenderised ENF compared with 57.1% of commercial ENF, and the storage time was another important factor in the rates of contamination. The extent of handling or manipulation of the enteral formula was critical in determining the level of contamination.

conclusionPreparation techniques for blenderised ENF need to be established and caregivers taught how to prepare and administer it appropriately in order to reduce contamination. Further, well-designed studies are required, which compare the microbial quality of blenderised ENF using adequate handling techniques and commercial ENF.

Indexed as

Enteral NutritionStaphylococcus aureusCross-Sectional StudiesEscherichia coliFood, FormulatedHumansaerobic plate countblenderised enteral nutrition formulacoliformenteral nutrition formulamicrobial qualitymicrobial safety

Identifiers

PMID33371227
PMCPMC7766503

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.