Evidence map›Paper›PMID 33371133›Full record

ArticleMedicine2020

Comparative efficacy and safety of traditional Chinese patent medicine in the treatment of Mycoplasma pneumoniae pneumonia in children: A protocol for systematic review and meta-analysis.

Hongan He, Xiao Wang, Yanyan Xiao, Jialin Zheng, Jinjuan Wang, Baoqing Zhang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  3. Article
  4. Article
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  6. Review
  7. The role of targeted regulation ofJournal of thoracic disease · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hongan HeThe First College of Clinical Medicine, Shandong University of Traditional Chinese Medicine.
Xiao WangThe First College of Clinical Medicine, Shandong University of Traditional Chinese Medicine.
Yanyan XiaoThe First College of Clinical Medicine, Shandong University of Traditional Chinese Medicine.
Jialin ZhengThe First College of Clinical Medicine, Shandong University of Traditional Chinese Medicine.
Jinjuan WangThe First College of Clinical Medicine, Shandong University of Traditional Chinese Medicine.
Baoqing ZhangThe Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, Shandong Province, China.ORCID 0000-0002-7166-1864

Funding

TCM Evidence-based Capacity 2019XZZX-EK004
6 · The paper itself

Abstract

backgroundMycoplasma pneumoniae pneumonia (MPP) is a common respiratory disease in children. Its incidence rate is increasing year by year. The drug resistance rate of macrolide antibiotics and other conventional treatment methods is higher, and there are limitations in clinical application. Traditional Chinese patent medicine (TCPM) is a powerful weapon to treat this disease. At present, there is no comparison of the safety and effectiveness of multiple TCPMs in the treatment of MPP in children. Therefore, we take the method of network meta-analysis to systematically compare the efficacy of various TCPMs in the treatment of this disease.

methodsWe will conduct comprehensive searches of Cochrane Library, PubMed, Web of Science, Clinical Trials, China National Knowledge Infrastructure, Chinese Scientific Journals Database, Chinese BioMedical Literature, Wanfang Database, and other electronic databases. The time frame is set from the establishment of the database to October 2020. All randomized controlled trials that meet the inclusion criteria will be included in this study. The 2 researchers will independently screen the literature according to the inclusion criteria, extract the data, and assess the bias risk of the included study. We will evaluate all the obtained data and evidence through Bayesian network meta-analysis, and use Stata 15.0 to process and analyze the data.

resultsThrough this study, we will evaluate the efficacy and safety of a variety of TCPMs for the treatment of MPP in children.

conclusionThe purpose of this study is to provide a strong reference for clinical application of TCPMs in the treatment of MPP in children, and to provide an important basis for clinicians to make correct judgments and put forward accurate treatment plans. ETHICS AND DISSEMINATION: This review does not involve any human or animal experiments and therefore does not require ethical approval. INPLASY REGISTRATION NUMBER: INPLASY 2020100108.

Indexed as

Anti-Bacterial AgentsDrugs, Chinese HerbalMacrolidesPneumonia, MycoplasmaAdolescentChildChild, PreschoolFemaleHumansInfantMaleMycoplasma pneumoniaeNetwork Meta-Analysis as TopicRandomized Controlled Trials as TopicResearch DesignSystematic Reviews as TopicAnti-Bacterial AgentsDrugs, Chinese HerbalMacrolides

Identifiers

PMID33371133
PMCPMC7748181

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.