Evidence map›Paper›PMID 33371016›Full record

ArticleBMJ open2020

Depressive symptoms and cardiovascular disease: a population-based study of older adults in rural Burkina Faso.

Ben Brinkmann, Collin F Payne, Iliana Kohler, Guy Harling, Justine Davies, Miles Witham, Mark J Siedner, Ali Sie, Mamadou Bountogo, Lucienne Ouermi and 2 more

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. Pooled it
  2. The Frequency ofThe application of clinical genetics · 2025
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  11. Impairment in Activities of Daily Living and Unmet Need for Care Among Older Adults: A Population-Based Study From Burkina Faso.The journals of gerontology. Series B, Psychological sciences and social sciences · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 8 institutions in 6 countries.

Ben BrinkmannHeidelberg Institute of Global Health, Heidelberg University, Heidelberg, Germany ben.brinkmann@stud.uni-heidelberg.de.ORCID 0000-0002-1726-5430
Collin F PayneSchool of Demography, The Australian National University, Canberra, Australian Capital Territory, Australia.
Iliana KohlerPopulation Studies Center (PSC) and Department of Sociology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Guy HarlingInstitute for Global Health, University College London, London, UK.ORCID 0000-0001-6604-491X
Justine DaviesInstitute of Applied Health Research, University of Birmingham, Birmingham, UK.
Miles WithamAGE Research Group, NIHR Newcastle Biomedical Research Centre, Newcastle University, Newcastle upon Tyne, UK.ORCID 0000-0002-1967-0990
Mark J SiednerDepartment of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.ORCID 0000-0003-3506-842X
Ali SieCentre de Recherche en Sante de Nouna, Nouna, Boucle du Mouhoun, Burkina Faso.
Mamadou BountogoCentre de Recherche en Sante de Nouna, Nouna, Boucle du Mouhoun, Burkina Faso.
Lucienne OuermiCentre de Recherche en Sante de Nouna, Nouna, Boucle du Mouhoun, Burkina Faso.
Boubacar CoulibalyCentre de Recherche en Sante de Nouna, Nouna, Boucle du Mouhoun, Burkina Faso.
Till BärnighausenHeidelberg Institute of Global Health, Heidelberg University, Heidelberg, Germany.
Centre de Recherche en Santé de Nouna · BFHeidelberg University · DEAustralian National University · AUHarvard University · USNewcastle upon Tyne Hospitals NHS Foundation Trust · GBUniversity of Birmingham · GBUniversity of Pennsylvania · USUniversity of the Witwatersrand · ZA

Funding

Leveraging Social Networks and Linkage to Care to Foster Healthy Aging in a Low-Income ContextR03AG069817 · NIA · UNIVERSITY OF PENNSYLVANIA · PI KOHLER, ILIANA V · 2020 to 2021
$162k
NIA NIH HHS R03 AG069817Wellcome TrustWellcome Trust 210479/Z/18/Z
6 · The paper itself

Abstract

objectivesTo contribute to the current understanding of depressive disorders in sub-Saharan African (SSA) countries by examining the association of depressive symptoms with cardiovascular and cardiometabolic conditions in a population-based study of middle-aged and older adults in rural Burkina Faso.

settingThis study was conducted in the Nouna Health and Demographic Surveillance System in north-western Burkina Faso, in a mixed rural and small-town environment. The data were obtained between May and July 2018.

participantsConsenting adults over 40 years of age (n=3026). PRIMARY AND SECONDARY OUTCOME MEASURES: Depressive symptoms were assessed using the Patient Health Questionnaire depression module (PHQ-9). Chronic cardiometabolic conditions were assessed via a lipid panel and glycated haemoglobin measures from serum, alongside anthropometry and blood pressure measurements and a self-reported questionnaire. Multivariable linear regression was used to test the relationship between depressive symptoms and cardiovascular/cardiometabolic conditions after controlling for sociodemographic factors.

resultsDepressive symptoms were not associated with the metabolic syndrome (standardised beta coefficient=0.00 (95% CI -0.04 to 0.03)), hypertension (beta=0.01 (95% CI -0.02 to 0.05)), diabetes mellitus (beta=0.00 (95% CI -0.04 to 0.04)) and past diagnosis of elevated blood pressure or blood sugar. Prior stroke diagnosis (beta=0.04 (95% CI 0.01 to 0.07)) or heart disease (beta=0.08 (95% CI 0.05 to 0.11)) was positively associated with the standardised PHQ-9 score as were self-reported stroke symptoms.

conclusionObjectively measured cardiometabolic conditions had no significant association with depressive symptoms in an older, poor, rural SSA population, in contrast to observations in high income countries. However, consequences of cardiovascular disease such as stroke and heart attack were associated with depressive symptoms in older adults in Burkina Faso.

Indexed as

Cardiovascular DiseasesHypertensionAgedBurkina FasoDepressionHumansMiddle AgedRisk FactorsRural Populationdepression & mood disordersepidemiologyhypertensionmental healthpublic healthstroke medicine

Identifiers

PMID33371016
PMCPMC7757460
OpenAlexW3106575573

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.