ArticleBMJ open respiratory research2020
Coronary heart disease and heart failure in asthma, COPD and asthma-COPD overlap.
Article in BMJ open respiratory research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 5 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
35 citing papers in PubMed, 5 syntheses or guidelines pooled it, 64 citations in OpenAlex.
- Risk Prediction Models for Hospital Readmission After Percutaneous Coronary Intervention: A Systematic Review and Meta-Analysis.Reviews in cardiovascular medicine · 2025Pooled it
- Modifiable risk factors that may be addressed in routine care to prevent progression to and extension of multimorbidity in people with COPD: a systematic literature review.BMJ open respiratory research · 2024Pooled it
- Association Between Asthma and All-Cause Mortality and Cardiovascular Disease Morbidity and Mortality: A Meta-Analysis of Cohort Studies.Frontiers in cardiovascular medicine · 2022Pooled it
- Asthma and the risk of cardiovascular diseases and mortality: a meta-analysis of cohort studies.Therapeutic advances in respiratory diseasePooled it
- Risk of Coronary Heart Disease in People with Chronic Obstructive Pulmonary Disease: A Meta-Analysis.International journal of chronic obstructive pulmonary diseasePooled it
- Risk factors for perioperative acute heart failure in older hip fracture patients and establishment of a nomogram predictive model.Journal of orthopaedic surgery and research · 2023Trial
- The Effects of Sequential Ventilation Therapy on Blood Gas Indexes, Pulmonary Function Indexes, Clinical Efficacy, and Safety in Patients with Severe Cor Pulmonale.Contrast media & molecular imaging · 2022Trial
- Chronic obstructive pulmonary disease and risk of incident cardiovascular disease, chronic kidney disease, and death: a systematic review and meta-analysis.EClinicalMedicine · 2026Article
- Asthma patients are at increased risk for adverse events and reoperation following posterior lumbar fusion.PloS one · 2026Article
- The association between asthma and heart failure - a systematic review and meta-analysis.European clinical respiratory journal · 2026Review
- Overlapping airway diseases and risk of major adverse cardiovascular events: a UK biobank prospective cohort study.Frontiers in cardiovascular medicine · 2026Article
- COPD-Asthma-Heart Failure Overlap: Optimizing Bronchodilators and ICS in a High-Risk Triad.Journal of asthma and allergy · 2026Review
- Associations of the Charlson comorbidity index with asthma and mortality (NHANES 2007-2018): a cross-sectional study.Journal of health, population, and nutrition · 2025Observational
- Asthma and extrapulmonary comorbidities in a middle-aged general population: results from the SCAPIS study.BMJ open respiratory research · 2025Article
- Impact of metoprolol combined with spironolactone on cardiac function in patients with coronary heart disease complicated by heart failure.American journal of translational research · 2025Article
- Cardiovascular Risk in Patients with Chronic Obstructive Pulmonary Disease: A Systematic Review.Journal of clinical medicine · 2024Review
- Genetic susceptibility to chronic diseases leads to heart failure among Europeans: the influence of leukocyte telomere length.Human molecular genetics · 2024Article
- Association between asthma and cardiovascular diseases: A longitudinal follow-up study using a national health screening cohort.The World Allergy Organization journal · 2024Article
- GOLD COPD DOCUMENT 2023: a brief update for practicing cardiologists.Clinical research in cardiology : official journal of the German Cardiac Society · 2024Review
- Exploring the association between asthma and chronic comorbidities: impact on clinical outcomes.Frontiers in medicine · 2024Review
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionWe investigated risk of coronary heart disease and heart failure in phenotypes of obstructive airway disease.
methodsAmong 91 692 participants in the Copenhagen General Population Study, 42 058 individuals were classified with no respiratory disease, and 11 988 individuals had different phenotypes of obstructive airways disease: asthma with early onset or late-onset, chronic obstructive pulmonary disease (COPD) with forced expiratory volume in one second (FEV
resultsDuring a mean follow-up of 5.7 years we registered 3584 admissions for coronary heart disease and 1590 admissions for heart failure. Multivariable Cox regression analyses of time to first admission were used with a two-sided p value of 0.05 as significance level. Compared with no respiratory disease the highest risks of coronary heart disease and heart failure were observed in ACO with late-onset asthma and FEV
conclusionsRisks of coronary heart disease and heart failure were increased in asthma, COPD and ACO. In asthma, the risk of coronary heart disease depended on presence of allergy. We suggest that cardiovascular risk factors should be assessed systematically in individuals with obstructive airway disease with the potential to facilitate targeted treatments.
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