Evidence map›Paper›PMID 33370995›Full record

ArticleBMJ case reports2020

Hypoxaemia and interstitial lung disease in an infant with hypothyroidism and hypotonia.

Melodie M Lynn, Dawn Simon, Ajay S Kasi

Open access · greenAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ case reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 3 pooled it
–field-weighted citation impact, top 72% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 syntheses or guidelines pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Melodie M LynnPediatrics, Emory University School of Medicine, Atlanta, Georgia, USA.
Dawn SimonPediatric Pulmonology, Emory University School of Medicine, Atlanta, Georgia, USA.
Ajay S KasiPediatric Pulmonology, Emory University School of Medicine, Atlanta, Georgia, USA ajay.kasi@emory.edu.ORCID http://orcid.org/0000-0003-0435-2807
Emory University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 7-month-old-term male infant presented with cough, tachypnoea, hypoxaemia and post-tussive emesis. Clinical history was significant for respiratory failure and pulmonary hypertension in the neonatal period requiring assisted ventilation, congenital hypothyroidism, mild hypotonia, recurrent respiratory infections, hypoxaemia requiring supplemental oxygen and nasogastric tube feeds. Physical examination showed tachypnoea, coarse bilateral breath sounds and mild hypotonia. Chest radiograph revealed multifocal pulmonary opacities with coarse interstitial markings and right upper lobe atelectasis. Following antibiotic therapy for suspected aspiration pneumonia, chest CT scan was performed and showed multiple areas of pulmonary consolidation and scattered areas of bilateral ground-glass opacities. Genetic studies showed a large deletion of chromosome 14q13.1-14q21.1, encompassing the NK2 homeobox 1 (

Indexed as

Chromosome DeletionAmoxicillin-Potassium Clavulanate CombinationAthetosisChoreaChromosomes, Human, Pair 14Congenital HypothyroidismEnteral NutritionFluid TherapyGenetic TestingHumansHypoxiaInfantIntubation, GastrointestinalLungMaleMuscle HypotoniaAmoxicillin-Potassium Clavulanate CombinationNKX2-1 protein, humanOxygenThyroid Nuclear Factor 1interstitial lung diseasepaediatricsthyroid disease

Identifiers

PMID33370995
PMCPMC7757479
OpenAlexW3118089347

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.