Trial reportClinical and experimental dental research2021
Caries arrest and lesion appearance using two different silver fluoride therapies on primary teeth with and without potassium iodide: 12-month results.
Trial report in Clinical and experimental dental research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 53 citations in OpenAlex.
- Comparative success of minimally invasive treatments for cavitated caries in primary teeth: a network meta-analysis.BMC oral health · 2025Pooled it
- Topical silver diamine fluoride (SDF) for preventing and managing dental caries in children and adults.The Cochrane database of systematic reviews · 2024Pooled it
- A randomized clinical trial of ammonia-free silver fluoride for treating cavitated dentine caries in primary teeth: adverse effects, short-term discolouration, and patient-reported outcomes.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026Trial
- Silver Diamine Fluoride vs Atraumatic Restoration for Managing Dental Caries in Schools: A Cluster Randomized Clinical Trial.JAMA network open · 2025Trial
- Caries arrest and lesion appearance using two different silver fluoride therapies on primary teeth with and without potassium iodide: 12-month results.Clinical and experimental dental research · 2021Trial
- Silver diamine fluoride for non-operative restorative treatment and prevention of dental caries.Canadian journal of dental hygiene : CJDH = Journal canadien de l'hygiene dentaire : JCHD · 2026Review
- Effect of nanosilver fluoride versus silver diamine fluoride on shear bond strength and color change of resin-modified glass ionomer cement bonded to artificial dentin caries: an in-vitro study.BMC oral health · 2026Article
- TheBiomaterial investigations in dentistry · 2026Article
- Review
- Comparison of Patient Acceptance and Caregiver Satisfaction of Glass-Ionomer Cement vs. Silver Fluoride/Potassium Iodide Application to Manage Molar Incisor Hypomineralisation Hypersensitivity Immediately and After 12 Weeks.Clinics and practice · 2025Article
- Improved Esthetics Using Silver Diamine Fluoride in the Management of Early Childhood Caries: A Case Series.Cureus · 2024Article
- Evaluation of staining potential of Silver Diamine Fluoride, Potassium Iodide, Nanosilver Fluoride: an in vitro study.BMC oral health · 2024Article
- Silver Diamine Fluoride Staining With Potassium Iodide: A Prospective Cohort Study.International dental journal · 2024Article
- Effects of silver diammine fluoride with/without potassium iodide on enamel and dentin carious lesions in primary teeth.Frontiers in oral health · 2024Article
- Physicochemical properties, biological chemistry and mechanisms of action of caries-arresting diammine-silver(I) fluoride and silver(I)-fluoride solutions for clinical use: a critical review.Frontiers in oral health · 2024Review
- Efficacy of Different Fluoride Therapies on Hypersensitive Carious Lesions in Primary Teeth.Medicina (Kaunas, Lithuania) · 2023Article
- A Silver Fluoride Intervention to Improve Oral Health Trajectories of Young Indigenous Australians: Protocol for a Cluster Randomized Controlled Trial.JMIR research protocols · 2023Article
- The Caries-Arrest Effectiveness of Silver Diamine Fluoride Treatment with Different Post-Treatment Instructions in Preschool Children: A Study Protocol for a Randomized Controlled Trial.Dentistry journal · 2023Article
- Influence of salivary acquired pellicle on colour changes and minerals content of dentine after application of silver diamine fluoride followed by potassium iodide.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2023Article
- Penetration of SDF and AgF from the infected dentine towards the unaffected tooth structure.Frontiers in oral health · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
backgroundGlobally, has been an increase in the use of silver fluoride products to arrest carious lesions and a variety of products are available.
objectivesTo examine differences in caries arrest and lesion colour of primary tooth carious lesions. MATERIAL AND
methodsA four-armed, parallel-design cluster-randomised controlled trial which investigated four protocols for caries arrest at 6m and 12m. Children in Group 1 and Group 2 received Rivastar Silver Diammine Fluoride (SDF), and children in Group 3 and Group 4 received a stabilised aqueous silver fluoride solution (AgF). Children in Group 2 and Group 4 received an additional application of KI immediately after the fluoride. Differences in caries arrest and lesion appearance were examined at 6m and 12m using two level logistic regression modelling.
resultsThe arrest rate varied by group membership; group 1 and group 3 had higher arrest rates (77.3% and 75.3% respectively) than group 2 and group 4 (65.4% and 51.2% respectively). The use of KI was also associated with lower odds of arrest (12m OR 0.25; CI 0.19, 0.34) and higher odds of avoiding black discolouration (12m OR 6.08; 2.36, 15.67).
conclusionsGlobally, has been an increase in the use of silver fluoride products to arrest carious lesions and a variety of products are available. This study demonstrated that both AgF and SDF can effectively arrest carious lesions on primary teeth. The use of KI is associated with poorer caries control but better aesthetic outcomes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.