Evidence map›Paper›PMID 33370563›Full record

ArticleThe Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases

Clinical and epidemiological aspects of Candidemia in eight medical centers in the state of Parana, Brazil: Parana Candidemia Network.

Carla Sakuma de Oliveira, Arnaldo Lopes Colombo, Elaine Cristina Francisco, Bernardo de Lima, Rinaldo F Gandra, Mariza Cristina Preifz de Carvalho, Cláudia Maria Dantas de Maia Carrilho, Renan Petinelli, Marsilene Pelison, Cesar Helbel and 7 more

Open access · goldAbstract read
In one paragraph

Article in The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
0.3field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Brazilian guidelines for the diagnosis and treatment of candidemia and invasive candidiasis in adults and children.The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases
    Guideline
  3. Preventive action of ketamine alone and in combination with antifungals on Candida biofilm formation in catheters.International microbiology : the official journal of the Spanish Society for Microbiology · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Changing Climate, ChangingJournal of fungi (Basel, Switzerland) · 2025
    Review
  8. Review
  9. Article
  10. Prevalence and Species Distribution ofJournal of fungi (Basel, Switzerland) · 2024
    Article
  11. Unresolved issues in the diagnosis of catheter related candidemia: A position paper.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2024
    Review
  12. Clinical, Epidemiological and Laboratory Features of InvasiveJournal of fungi (Basel, Switzerland) · 2023
    Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 7 institutions in 1 country.

Carla Sakuma de OliveiraHospital Universitário do Oeste do Paraná, Cascavel, PR, Brazil. Electronic address: csakuma21@yahoo.com.br.
Arnaldo Lopes ColomboUniversidade Federal de São Paulo, Laboratório Especial de Micologia, São Paulo, SP, Brazil.
Elaine Cristina FranciscoUniversidade Federal de São Paulo, Laboratório Especial de Micologia, São Paulo, SP, Brazil.
Bernardo de LimaHospital Universitário do Oeste do Paraná, Cascavel, PR, Brazil.
Rinaldo F GandraHospital Universitário do Oeste do Paraná, Cascavel, PR, Brazil.
Mariza Cristina Preifz de CarvalhoHospital do Câncer UOPECCAN, Cascavel, PR, Brazil.
Cláudia Maria Dantas de Maia CarrilhoHospital Universitário Regional Norte, Londrina, PR, Brazil.
Renan PetinelliHospital Universitário Regional Norte, Londrina, PR, Brazil.
Marsilene PelisonHospital Universitário Regional Norte, Londrina, PR, Brazil.
Cesar HelbelHospital Santa Casa de Maringá, Maringá, PR, Brazil.
Gerson CzelusniakHospital Universitário dos Campos Gerais, Ponta Grossa, PR, Brazil.
Hugo Manuel Paz MoralesHospital Erasto Gaertner, Curitiba, PR, Brazil.
Jamile Sardi PerozinHospital do Câncer de Londrina, Londrina, PR, Brazil.
Rosangela Lameira PinheiroHospital de Clínicas da Universidade Federal do Paraná, Setor de Micologia, Departamento de Saúde Coletiva, Curitiba, PR, Brazil.
Regielly CognialliHospital de Clínicas da Universidade Federal do Paraná, Setor de Micologia, Departamento de Saúde Coletiva, Curitiba, PR, Brazil.
Giovanni Luis BredaHospital de Clínicas da Universidade Federal do Paraná, Setor de Micologia, Departamento de Saúde Coletiva, Curitiba, PR, Brazil.
Flávio Queiroz-TellesHospital de Clínicas da Universidade Federal do Paraná, Setor de Micologia, Departamento de Saúde Coletiva, Curitiba, PR, Brazil.
Hospital de Clínicas Universidade Federal do Paraná · BRHospital Universitário Regional do Norte do Paraná · BRUniversidade Estadual do Oeste do Paraná · BRUniversidade Federal de São Paulo · BRHospital Erasto Gaertner · BRUniversidade Estadual de Londrina · BRUniversidade Estadual de Maringá · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesCandida spp. has been reported as one of the common agents of nosocomial bloodstream infections and is associated with a high mortality. Therefore, this study evaluated the clinical findings, local epidemiology, and microbiological aspects of candidemia in eight tertiary medical centers in the state of Parana, South of Brazil.

methodsIn this study, we reported 100 episodes of candidemia in patients admitted to eight different hospitals in five cities of the state of Parana, Brazil, using data collected locally (2016 and 2017) and tabulated online.

resultsThe incidence was found to be 2.7 / 1000 patients / day and 1.2 / 1000 admissions. C. albicans was responsible for 49% of all candidemia episodes. Cancer and surgery were the two most common underlying conditions associated with candidemia. The mortality rate within 30 days was 48%, and removal of the central venous catheter (p = 0.029) as well as empirical or prophylactic exposure to antifungals were both related to improved survival (p = 0.033).

conclusionsThis study highlights the high burden and mortality rates of candidemia in hospitals from Parana as well as the need to enhance antifungal stewardship program in the enrolled medical centers.

Indexed as

CandidemiaCross InfectionAntifungal AgentsBrazilCandidaHumansIncidenceAntifungal AgentsAntifungal resistanceCandida spp.EchinocandinsEpidemiology of candidemiaNosocomial infectionTriazoles

Identifiers

PMID33370563
PMCPMC9392142
OpenAlexW3115116022

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.