Evidence map›Paper›PMID 33370381›Full record

ArticlePloS one2020

3D printing direct to industrial roll-to-roll casting for fast prototyping of scalable microfluidic systems.

Amber L Boutiette, Cristoffer Toothaker, Bailey Corless, Chouaib Boukaftane, Caitlin Howell

Abstract read
In one paragraph

Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Augmented 3D Printing for Multiscale Microphysiological Systems.Small (Weinheim an der Bergstrasse, Germany) · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Amber L BoutietteDepartment of Chemical and Biomedical Engineering, University of Maine, Orono, Maine, United States of America.
Cristoffer ToothakerDepartment of Chemical and Biomedical Engineering, University of Maine, Orono, Maine, United States of America.
Bailey CorlessDepartment of Chemical and Biomedical Engineering, University of Maine, Orono, Maine, United States of America.
Chouaib BoukaftaneSappi North America, Inc., Westbrook, Maine, United States of America.
Caitlin HowellDepartment of Chemical and Biomedical Engineering, University of Maine, Orono, Maine, United States of America.ORCID 0000-0002-9345-6642

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microfluidic technologies have enormous potential to offer breakthrough solutions across a wide range of applications. However, the rate of scale-up and commercialization of these technologies has lagged significantly behind promising breakthrough developments in the lab, due at least in part to the problems presented by transitioning from benchtop fabrication methods to mass-manufacturing. In this work, we develop and validate a method to create functional microfluidic prototype devices using 3D printed masters in an industrial-scale roll-to-roll continuous casting process. There were no significant difference in mixing performance between the roll-to-roll cast devices and the PDMS controls in fluidic mixing tests. Furthermore, the casting process provided information on the suitability of the prototype microfluidic patterns for scale-up. This work represents an important step in the realization of high-volume prototyping and manufacturing of microfluidic patterns for use across a broad range of applications.

Indexed as

Lab-On-A-Chip DevicesEquipment DesignIndustryPrinting, Three-Dimensional

Identifiers

PMID33370381
PMCPMC7769481

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.