ArticlePloS one2020
Non-invasive myocardial work is reduced during transient acute coronary occlusion.
Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 17 citations in OpenAlex.
- Left Ventricular Mechanics in Multivessel Coronary Artery Disease with Versus Without Chronic Total Occlusion.Journal of cardiovascular development and disease · 2026Article
- Systemic blood pressure changes following coronary revascularization: towards a coronary baroreflex?European heart journal open · 2026Article
- Prognostic value of myocardial work indices measured on echocardiography in patients with aortic stenosis undergoing transcatheter aortic valve replacement: A systematic review and meta-analysis.Pakistan journal of medical sciences · 2026Article
- Shock index, modified shock index, and age-adjusted shock index for the prediction of impaired myocardial work in patients with ST-segment elevation myocardial infarction.Quantitative imaging in medicine and surgery · 2025Article
- Effect of Transcatheter Aortic Valve Implantation on Non-Invasive Myocardial Work Parameters: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2025Review
- Reduced myocardial work in Fontan circulation: feasibility, reproducibility, and diagnostic performance.European heart journal. Imaging methods and practice · 2025Article
- Identification and validation of the VEGF/p38MAPK/HSP27 pro-tumor inflammatory pathway: screening of active components fromFrontiers in immunology · 2025Article
- Intracardiac fluid dynamic analysis: available techniques and novel clinical applications.BMC cardiovascular disorders · 2024Review
- Usefulness of echocardiographic myocardial work in evaluating the microvascular perfusion in STEMI patients after revascularization.BMC cardiovascular disorders · 2022Article
- Non-Invasive Myocardial Work in Patients with Severe Aortic Stenosis.Journal of clinical medicine · 2022Article
- Echocardiographic Normal Reference Ranges for Non-invasive Myocardial Work Parameters in Pediatric Age: Results From an International Multi-Center Study.Frontiers in cardiovascular medicine · 2022Article
- Article
- Abnormal myocardial work in children with Kawasaki disease.Scientific reports · 2021Article
- Prediction of Significant Coronary Artery Disease Through Advanced Echocardiography: Role of Non-invasive Myocardial Work.Frontiers in cardiovascular medicine · 2021Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDuring ischemia a close relationship exists between sub-endocardial blood flow and myocardial function. Strain parameters can capture an impairment of regional longitudinal function but are load dependent. Recently, a novel non-invasive method to calculate Myocardial Work (MW) showed a strong correlation with invasive work measurements. Our aim was to investigate the ability of non-invasive MW indices to identify the ischaemic risk area during transient acute coronary occlusion (TACO). METHODS AND
resultsThe study population comprises 50 individuals with critical coronary stenosis (CCS). Echocardiography recordings were obtained before coronary angiography, during TACO and after revascularization to measure global longitudinal strain (GLS), Myocardial Work Index (MWI), Myocardial Constructive Work (MCW), Myocardial Wasted work (MWW), Myocardial work efficiency (MWE). Compared to baseline, we found a significant reduction of GLS (p = 0.005), MWI, MCW and MWE (p<0.001) during TACO.
conclusionsThe non-invasive measurement of MW parameters is a sensitive and early marker of myocardial ischemia during TACO.
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