ArticlePLoS neglected tropical diseases2020
Presence of pathogenic Leptospira spp. in the reproductive system and fetuses of wild boars (Sus scrofa) in Italy.
Article in PLoS neglected tropical diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- Human-to-human transmission of leptospirosis: a global systematic review.Frontiers in public health · 2026Pooled it
- A systematic review ofOne health (Amsterdam, Netherlands) · 2026Article
- Revisiting genital leptospirosis in large animals: impacts on reproductive health, diagnostic challenges, and future directions.Journal of clinical microbiology · 2026Review
- Molecular and serological detection ofFrontiers in veterinary science · 2026Article
- A Scoping Review of Antimicrobial Therapy inAnimals : an open access journal from MDPI · 2025Review
- Prevalence ofPathogens (Basel, Switzerland) · 2025Article
- Molecular typing and seroepidemiology of pathogenicIranian journal of veterinary research · 2025Article
- Foodborne Pathogens Across Different Food Matrices in Sicily (Southern Italy).Pathogens (Basel, Switzerland) · 2024Article
- Detection of Leptospira kirschneri in a short-beaked common dolphin (Delphinus delphis delphis) stranded off the coast of southern California, USA.BMC veterinary research · 2024Article
- Bovine Genital Leptospirosis: An Update of This Important Reproductive Disease.Animals : an open access journal from MDPI · 2024Review
- The Role of Wildlife and Pests in the Transmission of Pathogenic Agents to Domestic Pigs: A Systematic Review.Animals : an open access journal from MDPI · 2023Review
- Identification of PathogenicPathogens (Basel, Switzerland) · 2023Article
- Article
- Transient Presence of Live Leptospira interrogans in Murine Testes.Microbiology spectrum · 2022Article
- Article
- First detection of Leptospira santarosai in the reproductive track of a boar: A potential threat to swine production and public health.PloS one · 2022Article
- Article
- Presence and Characterization of Zoonotic Bacterial Pathogens in Wild Boar Hunting Dogs (Animals : an open access journal from MDPI · 2021Article
- Molecular Typing of PathogenicAnimals : an open access journal from MDPI · 2021Article
- Article
Corrections and comments
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Authors and funding
13 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Leptospirosis is a re-emerging and globally spread zoonosis caused by pathogenic genomospecies of Leptospira. Wild boar (Sus scrofa) are an important Leptospira host and are increasing in population all over Europe. The aim of this investigation was to evaluate Leptospira spp. infection in the reproductive systems of wild boar hunted in two Italian regions: Tuscany and Sardinia. From 231 animals, reproductive system tissue samples (testicles, epididymides, uteri) as well as placentas and fetuses were collected. Bacteriological examination and Real-Time PCR were performed to detect pathogenic Leptospira (lipL32 gene). Leptospires were isolated from the testicles and epididymides of one adult and two subadult wild boar. Four isolates from the two subadult males were identified as Leptospira interrogans serogroup Australis by MLST, whereas Leptospira kirschneri serogroup Grippotyphosa was identified from the adult testicles and epididymis. Using Real-Time PCR, 70 samples were positive: 22 testicles (23.16%) and 22 epididymides (23.16%), 10 uteri (7.35%), 3 placentas (6.66%), and 13 fetuses (28.88%). Amplification of the rrs2 gene identified L. interrogans and L. kirschneri species. The results from this investigation confirmed that wild boar represent a potential source of pathogenic Leptospira spp. Isolation of Leptospira serogroups Australis and Grippotyphosa from the male reproductive system and the positive Real-Time PCR results from both male and female samples could suggest venereal transmission, as already demonstrated in pigs. Furthermore, placentas and fetuses were positive for the lipL32 target, and this finding may be related to a possible vertical transmission of pathogenic Leptospira.
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