Trial reportJournal of consulting and clinical psychology2020
Psychiatric outcomes following severe deprivation in early childhood: Follow-up of a randomized controlled trial at age 16.
Trial report in Journal of consulting and clinical psychology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.
- Genetic and Environmental Risk Factors for Intermittent Explosive Disorder, ADHD and Conduct Disorder: Shared and Unique Influences.Clinical psychology & psychotherapyPooled it
- Adaptive functioning at age 18 years following severe early deprivation: Results of a randomized controlled trial.Developmental psychology · 2026Trial
- Early Life Stress Impairs VTA Coordination of BLA Network and Behavioral States.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Toward a multi-level approach to the study of the intergenerational transmission of trauma: Current findings and future directions.Development and psychopathology · 2024Review
- Article
- Child maltreatment and youth suicide risk: A developmental conceptual model and implications for suicide prevention.Development and psychopathology · 2023Article
- Exploratory study evaluating the relationships between perinatal adversity, oxidative stress, and infant neurodevelopment across the first year of life.PLOS global public health · 2023Article
- The Bucharest Early Intervention Project: Adolescent mental health and adaptation following early deprivation.Child development perspectives · 2022Article
- Internet-Based Prevention Program of Victimization for Youth in Care and Care Leavers (EMPOWER YOUTH): Protocol for a Randomized Controlled Trial.JMIR research protocols · 2022Article
- The effects of early life adversity on children's mental health and cognitive functioning.Translational psychiatry · 2022Review
- Children's Attention and Self-Regulatory Behavior Before and During the COVID-19 Pandemic.Journal of developmental and behavioral pediatrics : JDBP · 2022Article
- The impact of the environment on neurodevelopmental disorders in early childhood.Jornal de pediatriaReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 6 institutions in 3 countries.
Funding
Abstract
objectiveEarly psychosocial deprivation is associated with increased risk for psychopathology, yet few studies have examined outcomes in adolescents.
methodAt baseline (M age 22 months), 136 children from Bucharest, Romania, living in large institutions, were randomized into foster care (FCG) or to care as usual (CAUG). Caregivers completed psychiatric interviews regarding their children (52 FCG; 51 CAUG) at age 16 years (M = 16.67 years; SD = 0.78) to assess past year diagnoses and symptom counts. In addition, never-institutionalized community comparison children (n = 47) were included.
resultsEver-institutionalized children had higher rates of meeting criteria for any psychiatric disorder and higher symptom counts of internalizing, externalizing, attention-deficit/hyperactivity, and substance use disorders compared to never-institutionalized children (ps < .05). Using intent-to-treat analyses, we found that children in the CAUG had more than twice the rate of psychiatric disorders than children in the FCG (OR = 2.48, 95% CI [1.12, 5.48]). Furthermore, children in foster care who remained in their original placement did not significantly differ in their rates of psychiatric disorders compared to never-institutionalized children.
conclusionsThere are many ways children can be separated from parents, including placement into institutional care. The current findings indicate that such placements are associated with significant risks for psychopathology. Moreover, we provide causal evidence for the long-lasting positive effect of foster care in reducing the risk of psychopathology in adolescence, especially among those in stable placements. These results provide strong evidence that early and stable placements into quality foster care may mitigate risk for psychopathology following severe early psychosocial deprivation. (PsycInfo Database Record (c) 2020 APA, all rights reserved).
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