Evidence map›Paper›PMID 33370110›Full record

ArticleJournal of the American Society for Mass Spectrometry2021

Localization of Carbon-Carbon Double Bond and Cyclopropane Sites in Cardiolipins via Gas-Phase Charge Inversion Reactions.

Caitlin E Randolph, De'Shovon M Shenault, Stephen J Blanksby, Scott A McLuckey

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Society for Mass Spectrometry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
  2. Structural Elucidation of Phosphatidylcholines via Radical-Directed Dissociation of [M + CuJournal of the American Society for Mass Spectrometry · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Recent Advances in Gas-phase Ion/Ion Chemistry for Lipid Analysis.Trends in analytical chemistry : TRAC · 2023
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Caitlin E RandolphDepartment of Chemistry, Purdue University, West Lafayette, Indiana 47907-2084, United States.
De'Shovon M ShenaultDepartment of Chemistry, Purdue University, West Lafayette, Indiana 47907-2084, United States.
Stephen J BlanksbyCentral Analytical Research Facility, Institute for Future Environments, Queensland University of Technology, Brisbane, QLD 4000, Australia.ORCID http://orcid.org/0000-0002-8560-756X
Scott A McLuckeyDepartment of Chemistry, Purdue University, West Lafayette, Indiana 47907-2084, United States.ORCID http://orcid.org/0000-0002-1648-5570
Purdue University West Lafayette · USQueensland University of Technology · AU

Funding

Gas-phase Bio-conjugation in the Tandem Mass Spectrometry of Peptides, Proteins,R37GM045372 · NIGMS · PURDUE UNIVERSITY · PI MCLUCKEY, SCOTT A · 2014 to 2023
$3.1M
Mass spectrometry method with C=C location specificity for qualitative and quantitative lipid analysisR01GM118484 · NIGMS · PURDUE UNIVERSITY · PI MCLUCKEY, SCOTT A · 2016 to 2020
$1.6M
NIGMS NIH HHS R01 GM118484NIGMS NIH HHS R37 GM045372
6 · The paper itself

Abstract

Cardiolipins (CLs) are comprised of two phosphatic acid moieties bound to a central glycerol backbone and are substituted with four acyl chains. Consequently, a vast number of distinct CL structures are possible in different biological contexts, representing a significant analytical challenge. Electrospray ionization tandem mass spectrometry (ESI-MS/MS) has become a widely used approach for the detection, characterization, and quantitation of complex lipids, including CLs. Central to this approach is fragmentation of the [CLs - H]

Identifiers

PMID33370110
PMCPMC8557092
OpenAlexW3114039552

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.