Trial reportPhysiological reports2021
High-intensity interval training and essential amino acid supplementation: Effects on muscle characteristics and whole-body protein turnover.
Trial report in Physiological reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.
- Pooled it
- Cardiorespiratory Fitness and Performance Adaptations to High-Intensity Interval Training: Are There Differences Between Men and Women? A Systematic Review with Meta-Analyses.Sports medicine (Auckland, N.Z.) · 2024Pooled it
- High-intensity interval training and essential amino acid supplementation: Effects on muscle characteristics and whole-body protein turnover.Physiological reports · 2021Trial
- Review
- Does High-Intensity Interval Training Increase Muscle Strength, Muscle Mass, and Muscle Endurance? A Systematic Review and Meta-Analysis.Sports (Basel, Switzerland) · 2025Review
- Impact of a Four-Week NCAA-Compliant Pre-Season Strength and Conditioning Program on Body Composition in NCAA Division II Women's Basketball.Journal of functional morphology and kinesiology · 2025Article
- Effect of training status on muscle excitation and neuromuscular fatigue with resistance exercise with and without blood flow restriction in young men.Physiological reports · 2025Article
- Strategies for Improving Firefighter Health On-Shift: A Review.Journal of functional morphology and kinesiology · 2024Review
- Impact of low-load resistance exercise with and without blood flow restriction on muscle strength, endurance, and oxidative capacity: A pilot study.Physiological reports · 2024Article
- International Society of Sports Nutrition Position Stand: Effects of essential amino acid supplementation on exercise and performance.Journal of the International Society of Sports Nutrition · 2023Article
- Sex Differences Across the Life Course: A Focus On Unique Nutritional and Health Considerations among Women.The Journal of nutrition · 2022Article
- Functional Properties of Meat in Athletes' Performance and Recovery.International journal of environmental research and public health · 2022Review
- Physical Fitness Recovery of Athletes Based on High-Intensity Sports Intermittent Training.BioMed research international · 2022Article
- Metabolic effects of high-intensity interval training and essential amino acids.European journal of applied physiology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 3 institutions in 1 country.
Funding
Abstract
The purpose of this study was to compare the independent and combined effects of high-intensity interval training (HIIT) and essential amino acids (EAA) on lean mass, muscle characteristics of the quadriceps, and 24-hr whole-body protein turnover (WBPT) in overweight and obese adults. An exploratory aim was to evaluate potential modulatory effects of sex. Sixty-six adults (50% female; Age: 36.7 ± 6.0 yrs; %BF: 36.0 ± 7.8%) were assigned to 8 wks of: (a) HIIT, 2 days/wk; (b) EAA supplementation, 3.6 g twice daily; (c) HIIT + EAA; or (d) control. At baseline, 4 wks, and 8 wks, total body, thigh LM and muscle characteristics were measured via dual-energy x-ray absorptiometry and B-mode ultrasound, respectively. In a subsample, changes in WBPT was measured using [N
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.