Evidence map›Paper›PMID 33369256›Full record

ArticleInfluenza and other respiratory viruses2021

Evidence for an increase in the intensity of inter-seasonal influenza, Queensland, Australia, 2009-2019.

Elenor J Kerr, Jonathan Malo, Kaitlyn Vette, Graeme R Nimmo, Stephen B Lambert

Open access · goldAbstract read
In one paragraph

Article in Influenza and other respiratory viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Respiratory virus detection during the COVID-19 pandemic in Queensland, Australia.Australian and New Zealand journal of public health · 2022
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Elenor J KerrNational Centre for Epidemiology and Population Health, Australian National University, Canberra, ACT, Australia.ORCID 0000-0002-6403-2701
Jonathan MaloCommunicable Diseases Branch, Queensland Health, Brisbane, Qld, Australia.
Kaitlyn VetteNational Centre for Immunisation Research and Surveillance, Sydney, NSW, Australia.
Graeme R NimmoPathology Queensland, Queensland Health, Brisbane, Qld, Australia.
Stephen B LambertNational Centre for Epidemiology and Population Health, Australian National University, Canberra, ACT, Australia.
Australian National University · AUQueensland Health · AUNational Centre for Immunisation Research & Surveillance · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInter-seasonal influenza cases have been increasing in Australia. Studies of influenza seasonality typically focus on seasonal transmission in temperate regions, leaving our understanding of inter-seasonal epidemiology limited. We aimed to improve understanding of influenza epidemiology during inter-seasonal periods across climate zones, and explored influenza intensity and strain dominance patterns over time.

methodsQueensland state-wide laboratory-confirmed influenza notifications and public laboratory influenza test data from 2009-2019 were described by demographics, time period, region and strain type. We compared influenza intensity over time using the WHO Average Curve method to provide thresholds for seasonal and inter-seasonal periods.

resultsAmong the 243 830 influenza notifications and 490 772 laboratory tests reported in Queensland between 2009 and 2019, 15% of notifications and 40% of tests occurred during inter-seasonal periods, with 6.3% of inter-seasonal tests positive. Inter-seasonal notifications and tests substantially increased over time and increases in weekly proportions positive and intensity classifications suggested gradual increases in virus activity. Tropical inter-seasonal activity was higher with periods of marked increase. Influenza A was dominant, although influenza B represented up to 72% and 42% of notifications during some seasonal and inter-seasonal periods, respectively.

conclusionsUsing notification and testing data, we have demonstrated a gradual increase in inter-seasonal influenza over time. Our findings suggest this increase results from an interplay between testing, activity and intensity, and strain circulation. Seasonal intensity and strain circulation appeared to modify subsequent period intensity. Routine year-round surveillance data would provide a better understanding of influenza epidemiology during this infrequently studied inter-seasonal time period.

Indexed as

Influenza, HumanAustraliaClimateHumansQueenslandSeasonsAustraliaepidemiologyhumaninfluenzainter-seasonalityseasonssurveillance

Identifiers

PMID33369256
PMCPMC8051720
OpenAlexW3113672192

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.