Evidence map›Paper›PMID 33369107›Full record

ArticleJournal of cellular and molecular medicine2021

Predictive value of protease-activated receptor-2 (PAR

Shengnan He, Meiquan Xu, Zhen Xiong, Ye Hu, Qin Huo, Jingxiao Lu, Yuntao Lin, Lan Yang

Open access · goldAbstract read
In one paragraph

Article in Journal of cellular and molecular medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Article
  6. The role of cellular proteostasis in antitumor immunity.The Journal of biological chemistry · 2022
    Review
  7. Article
  8. Predictive value of protease-activated receptor-2 (PARJournal of cellular and molecular medicine · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Shengnan HeBiobank of Shenzhen Second People's Hospital, Health Science Center, Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University, Shenzhen, China.
Meiquan XuPathology Department of Shenzhen Second People's Hospital, Health Science Center, Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University, Shenzhen, China.
Zhen XiongWuhan Children's Hospital, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, China.
Ye HuBiobank of Shenzhen Second People's Hospital, Health Science Center, Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University, Shenzhen, China.
Qin HuoBiobank of Shenzhen Second People's Hospital, Health Science Center, Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University, Shenzhen, China.
Jingxiao LuBiobank of Shenzhen Second People's Hospital, Health Science Center, Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University, Shenzhen, China.
Yuntao LinDepartment of Oral and Maxillofacial Surgery, Peking University Shenzhen Hospital, Shenzhen, China.
Lan YangBiobank of Shenzhen Second People's Hospital, Health Science Center, Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University, Shenzhen, China.ORCID 0000-0002-0798-4482
Shenzhen Second People's Hospital · CNPeking University · CNWuhan Children's Hospital · CN

Funding

Guangdong Basic and Applied Basic Research Foundation 2020A1515010112National Natural Science Foundation of China 81672813National Natural Science Foundation of China 81972202Sanming Project of Medicine in Shenzhen SZXJ2017076Science, Technology and Innovation Commission of Shenzhen Municipality JCYJ20180507184647104Shenzhen City Science and Technology Development Projects JCYJ20190806164212825
6 · The paper itself

Abstract

Metastasis is the primary cause of an unfavourable prognosis in patients with malignant cancer. Over the last decade, the role of proteinases in the tumour microenvironment has attracted increasing attention. As a sensor of proteinases, proteinase-activated receptor 2 (PAR

Indexed as

Biomarkers, TumorAdultCell Line, TumorDisease SusceptibilityFemaleGene Expression ProfilingHumansKaplan-Meier EstimateMiddle AgedNeoplasm GradingNeoplasm StagingPrognosisReceptor, PAR-2ROC CurveTranscriptomeTumor MicroenvironmentBiomarkers, TumorF2RL1 protein, humanReceptor, PAR-2cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC)Grb-associated binding protein 2 (Gab2)metastasismiR-125bprotease-activated receptor 2 (PAR2)

Identifiers

PMID33369107
PMCPMC7875903
OpenAlexW3117661308

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.