Evidence map›Paper›PMID 33368958›Full record

ArticleColorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland2021

National variation in pulmonary metastasectomy for colorectal cancer.

Hayley M Fenton, Paul J Finan, Richard Milton, Michael Shackcloth, John C Taylor, Tom Treasure, Eva J A Morris

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. The Pulmonary Metastasectomy in Colorectal Cancer cohort study: Analysis of case selection, risk factors and survival in a prospective observational study of 512 patients.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2021
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Hayley M FentonCancer Epidemiology Group, Leeds Institute for Data Analytics, University of Leeds, Leeds, UK.ORCID 0000-0001-7824-2614
Paul J FinanCancer Epidemiology Group, Leeds Institute for Data Analytics, University of Leeds, Leeds, UK.
Richard MiltonDepartment of Thoracic Surgery, St James's University Hospital, Leeds, UK.
Michael ShackclothDepartment of Thoracic Surgery, Liverpool Heart and Chest Hospital, Liverpool, UK.
John C TaylorCancer Epidemiology Group, Leeds Institute for Data Analytics, University of Leeds, Leeds, UK.ORCID 0000-0002-2518-5799
Tom TreasureClinical Operational Research Unit, University College London, London, UK.
Eva J A MorrisNuffield Department of Population Health, Big Data Institute, University of Oxford, Oxford, UK.
University of Leeds · GBSt James's University Hospital · GBUniversity College London · GBUniversity of Liverpool · GBUniversity of Oxford · GB

Funding

Cancer Research UK A23706Medical Research Council MR/L01629X/1Yorkshire Cancer Research L394
6 · The paper itself

Abstract

aimEvidence on patterns of use of pulmonary metastasectomy in colorectal cancer patients is limited. This population-based study aims to investigate the use of pulmonary metastasectomy in the colorectal cancer population across the English National Health Service (NHS) and quantify the extent of any variations in practice and outcome.

methodsAll adults who underwent a major resection for colorectal cancer in an NHS hospital between 2005 and 2013 were identified in the COloRECTal cancer data Repository (CORECT-R). All inpatient episodes corresponding to pulmonary metastasectomy, occurring within 3 years of the initial colorectal resection, were identified. Multi-level logistic regression was used to determine patient and organizational factors associated with the use of pulmonary metastasectomy for colorectal cancer, and Kaplan-Meier and Cox models were used to assess survival following pulmonary metastasectomy.

resultsIn all, 173 354 individuals had a major colorectal resection over the study period, with 3434 (2.0%) undergoing pulmonary resection within 3 years. The frequency of pulmonary metastasectomy increased from 1.2% of patients undergoing major colorectal resection in 2005 to 2.3% in 2013. Significant variation was observed across hospital providers in the risk-adjusted rates of pulmonary metastasectomy (0.0%-6.8% of patients). Overall 5-year survival following pulmonary resection was 50.8%, with 30-day and 90-day mortality of 0.6% and 1.2% respectively.

conclusionsThis study shows significant variation in the rates of pulmonary metastasectomy for colorectal cancer across the English NHS.

Indexed as

Colorectal NeoplasmsLung NeoplasmsMetastasectomyAdultHumansPrognosisProportional Hazards ModelsRetrospective StudiesState MedicineSurvival Ratecolorectal cancerpulmonary metastasectomypulmonary metastases

Identifiers

PMID33368958
PMCPMC8614123
OpenAlexW3117523873

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.