ArticleJournal of genetic counseling2021
GeneLiFT: A novel test to facilitate rapid screening of genetic literacy in a diverse population undergoing genetic testing.
Article in Journal of genetic counseling, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
22 citing papers in PubMed, 31 citations in OpenAlex.
- Schoolhouse risk: Can we mitigate the polygenic Pygmalion effect?Acta psychologica · 2024Trial
- Neighborhood Opportunity and Genetic Literacy in a Representative Sample of US Adults.Prevention science : the official journal of the Society for Prevention Research · 2026Article
- Genetic disorders and associated morbidity, mortality, and congenital anomalies in preterm infants born at less than 34 weeks of gestation.BMC pediatrics · 2025Observational
- Developing a questionnaire to explore lay people's preferences for communicating hereditary conditions within families: insights from a cognitive interview study.Journal of community genetics · 2025Article
- Knowledge, attitudes and demand toward cardiovascular polygenic risk testing in clinical practice: cross-sectional survey of patients.European journal of human genetics : EJHG · 2025Article
- Development and evaluation of patient-centred polygenic risk score reports for glaucoma screening.BMC medical genomics · 2025Article
- Evaluating the Applied Knowledge of BRCA Testing among Spanish-Preferring Latino Americans: The Influence of Acculturation and Literacy.Public health genomics · 2025Article
- Negative results from DNA-based population screening for adult-onset diseases: the recipients' experience.Journal of community genetics · 2024Article
- Variability in conceptualizations and measurement of genetic literacy.PEC innovation · 2023Article
- Readiness for Parkinson's disease genetic testing and counseling in patients and their relatives in urban settings in the Dominican Republic.NPJ Parkinson's disease · 2023Article
- Defining orienting language in the genetic counseling process.Journal of genetic counseling · 2023Article
- The effect of genetic education on the referral of patients to genetic evaluation: Findings from a national survey of nephrologists.Genetics in medicine : official journal of the American College of Medical Genetics · 2023Article
- Public attitudes toward cloud computing and willingness to share personal health records (PHRs) and genome data for health care research in Japan.Human genome variation · 2023Article
- Article
- Understanding changes in genetic literacy over time and in genetic research participants.American journal of human genetics · 2022Article
- The New Precision Stewards?Journal of personalized medicine · 2022Article
- The Impact of Proband Indication for Genetic Testing on the Uptake of Cascade Testing Among Relatives.Frontiers in genetics · 2022Article
- Australian human research ethics committee members' confidence in reviewing genomic research applications.European journal of human genetics : EJHG · 2021Article
- Physician Communication and Patient Understanding of Molecular Testing Terminology.The oncologist · 2021Article
- GeneLiFT: A novel test to facilitate rapid screening of genetic literacy in a diverse population undergoing genetic testing.Journal of genetic counseling · 2021Article
Corrections and comments
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Authors and funding
13 authors at 1 institution in 1 country.
Funding
Abstract
With the broader introduction of genomic medicine in research and clinical care, an increasing number of persons are offered genetic testing. Many factors, including genetic literacy, may impact the utilization of genetic results by patients and their families. We developed a rapid, self-administered measure of genetic literacy, called Genetic Literacy Fast Test (GeneLiFT). We next evaluated the association of GeneLiFT scores with the comprehension of limitations of genomic medicine in participants undergoing genetic testing in the NIH-sponsored eMERGE III study at Columbia University Irving Medical Center, New York. All participants underwent genetic screening for variants in 74 actionable genes associated with adult-onset disorders. A diverse cohort of 724 participants completed the survey (60% women, 45% less than 40 years old, and 53% self-reported White non-Hispanic ancestry). The GeneLiFT was validated using known group differences based on education, health literacy, and numeracy, and with questions assessing genetic knowledge. GeneLiFT identified multiple standard genetics terms, that is, jargon, not recognized by more than 50% of participants (including actionability and pathogenicity). Low genetic literacy, identified in 210 participants (29%), was significantly associated with poor understanding of the limitations of genetic testing (p-values < 10
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.