Evidence map›Paper›PMID 33368788›Full record

ReviewReviews in medical virology2021

Classical and alternative receptors for SARS-CoV-2 therapeutic strategy.

Siti Fathiah Masre, Nurul Farhana Jufri, Farah Wahida Ibrahim, Sayyidi Hamzi Abdul Raub

Open access · bronzeAbstract readReview
In one paragraph

Review in Reviews in medical virology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
1.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 60 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
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  7. Article
  8. Article
  9. Review
  10. The role of dendritic cells in COVID-19 infection.Emerging microbes & infections · 2023
    Review
  11. Review
  12. Review
  13. Review
  14. Article
  15. Review
  16. Review
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  18. Review
  19. Animal models for COVID-19: advances, gaps and perspectives.Signal transduction and targeted therapy · 2022
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Siti Fathiah MasreFaculty of Health Sciences, Centre for Toxicology and Health Risk Studies, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.ORCID https://orcid.org/0000-0002-4202-2289
Nurul Farhana JufriFaculty of Health Sciences, Centre for Toxicology and Health Risk Studies, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.
Farah Wahida IbrahimFaculty of Health Sciences, Centre for Toxicology and Health Risk Studies, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.
Sayyidi Hamzi Abdul RaubPantai Premier Pathology SDN BHD, Reference Specialised Laboratory, Pantai Hospital Kuala Lumpur, Kuala Lumpur, Malaysia.
University Kebangsaan Malaysia Medical Centre · MYHospital Kuala Lumpur · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Understanding the molecules that are essential for severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) entry can provide insights into viral infection and dissemination. Recently, it has been identified from several studies that angiotensin-converting enzyme 2 receptor and transmembrane serine protease 2 are the main entry molecules for the SARS-CoV-2, which produced the pandemic of Covid-19. However, additional evidence showed several other viral receptors and cellular proteases that are also important in facilitating viral entry and transmission in the target cells. In this review, we summarized the types of SARS-CoV-2 entry molecules and discussed their crucial roles for virus binding, protein priming and fusion to the cellular membrane important for SARS-CoV-2 infection.

Indexed as

Angiotensin-Converting Enzyme 2AnimalsCOVID-19COVID-19 Drug TreatmentHumansReceptors, VirusSARS-CoV-2Virus InternalizationAngiotensin-Converting Enzyme 2Receptors, VirusACE2Covid-19entry moleculeSARS-CoV-2TMPRSS2

Identifiers

PMID33368788
PMCPMC7883063
OpenAlexW3115952386

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.