Evidence map›Paper›PMID 33368766›Full record

ArticleJournal of cardiovascular electrophysiology2021

Ablation guided by STAR-mapping in addition to pulmonary vein isolation is superior to pulmonary vein isolation alone or in combination with CFAE/linear ablation for persistent AF.

Shohreh Honarbakhsh, Richard J Schilling, Rui Providencia, Gurpreet Dhillon, Omotomilola Bajomo, Emily Keating, Malcolm Finlay, Ross J Hunter

Open access · hybridAbstract read
In one paragraph

Article in Journal of cardiovascular electrophysiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. State of the Art of Artificial Intelligence in Clinical Electrophysiology in 2025: A Scientific Statement of the European Heart Rhythm Association (EHRA) of the ESC, the Heart Rhythm Society (HRS), and the ESC Working Group on E-Cardiology.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025
    Article
  3. Article
  4. Review
  5. Article
  6. AI in the EP lab - mapping, imaging, and signal interpretation.Indian pacing and electrophysiology journal
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Shohreh HonarbakhshBarts Heart Centre, Barts Health NHS Trust, London, UK.ORCID 0000-0003-0081-5739
Richard J SchillingBarts Heart Centre, Barts Health NHS Trust, London, UK.
Rui ProvidenciaBarts Heart Centre, Barts Health NHS Trust, London, UK.
Gurpreet DhillonBarts Heart Centre, Barts Health NHS Trust, London, UK.
Omotomilola BajomoBarts Heart Centre, Barts Health NHS Trust, London, UK.
Emily KeatingBarts Heart Centre, Barts Health NHS Trust, London, UK.
Malcolm FinlayBarts Heart Centre, Barts Health NHS Trust, London, UK.
Ross J HunterBarts Heart Centre, Barts Health NHS Trust, London, UK.
Barts Health NHS Trust · GBQueen Mary University of London · GB

Funding

British Heart Foundation PG/16/10/32016
6 · The paper itself

Abstract

introductionThe optimal ablation approach for persistent atrial fibrillation (AF) remains unclear. METHODS AND

resultsObjective was to compare the long-term rates of freedom from AF/AT in patients that underwent STAR mapping guided ablation against outcomes of patients undergoing conventional ablation procedures. Patients undergoing ablation for persistent AF as part of the Stochastic Trajectory Analysis of Ranked signals (STAR) mapping study were included. Outcomes following 'pulmonary vein isolation (PVI) plus STAR mapping guided ablation (STAR mapping cohort) were compared to patients undergoing PVI alone ablation during the same time period and also a propensity-matched cohort undergoing PVI plus the addition of complex fractionated electrogram (CFAE) and/or linear ablation ("conventional ablation"). Rates of procedural AF termination and freedom from AF/AT during follow-up were compared. Sixty-five patients were included in both the STAR cohort and propensity matched conventional ablation cohort. AF termination rates were significantly higher in the STAR cohort (51/65, 78.5%) than conventional ablation cohort (10/65, 15.4%) and PVI alone ablation cohort (13/50, 26.0%; STAR cohort vs. other 2 cohorts both p < .001). There was no significant difference in procedure time between the three cohorts. During ≥20 months follow-up a lower proportion of patients had AF/AT recurrence in the STAR cohort (20.0%) compared with the conventional ablation cohort (50.8%) or the PVI alone ablation cohort (50.0%; both p < .05 compared to STAR cohort).

conclusionsOutcomes of PVI plus STAR mapping guided ablation was superior to PVI alone or in combination with linear/CFAE ablation. A multicenter randomized controlled trial is planned to confirm these findings.

Indexed as

Atrial FibrillationCatheter AblationPulmonary VeinsHumansRecurrenceTreatment Outcomeatrial fibrillationcatheter ablationmappingpulmonary vein isolation

Identifiers

PMID33368766
PMCPMC8607469
OpenAlexW3113920854

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.