ArticleJournal of veterinary internal medicine2021
Evaluation of 3 refractometers to determine transfer of passive immunity in neonatal beef calves.
Article in Journal of veterinary internal medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 29 citations in OpenAlex.
- Evaluating the feasibility of using digital Brix refractometry to determine the passive immune status of lambs.The Veterinary record · 2026Article
- Failure of Passive Immune Transfer in Neonatal Beef Calves: A Scoping Review.Animals : an open access journal from MDPI · 2025Review
- Determination of the Reliability and Accuracy of the Brix Refractometer for the Detection of Colostrum Quality in Sheep.Veterinary medicine and science · 2025Article
- Factors associated with failure of passive transfer of immunity and morbidity in spring-born beef and dairy calves during the first 30 days of life.Frontiers in veterinary science · 2025Article
- Effect of suckler cow breed type and parity on the development of the cow-calf bond post-partum and calf passive immunity.Irish veterinary journal · 2024Article
- Evaluation of an immunochromatographic point-of-care test for the detection of failure of transfer of passive immunity in calves.Acta veterinaria Scandinavica · 2023Article
- Local and Systemic Antibody Responses in Beef Calves Vaccinated with a Modified-Live Virus Bovine Respiratory Syncytial Virus (BRSV) Vaccine at Birth following BRSV Infection.Veterinary sciences · 2022Article
- Maternal Behavior in Beef Cattle: The Physiology, Assessment and Future Directions-A Review.Veterinary sciences · 2022Review
- Concentration and heritability of immunoglobulin G and natural antibody immunoglobulin M in dairy and beef colostrum along with serum total protein in their calves.Journal of animal science · 2022Article
- Assessment of a Rapid Semi-Quantitative Immunochromatographic Test for the Evaluation of Transfer of Passive Immunity in Calves.Animals : an open access journal from MDPI · 2021Article
- Evaluation of 3 refractometers to determine transfer of passive immunity in neonatal beef calves.Journal of veterinary internal medicine · 2021Article
- Comparison of turbidometric immunoassay, refractometry, and gamma-glutamyl transferase to radial immunodiffusion for assessment of transfer of passive immunity in high-risk beef calves.Journal of veterinary internal medicineArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
Abstract
backgroundRefractometry is used to assess transfer of passive immunity (TPI), but studies evaluating different refractometers and appropriate thresholds for recommended target immunoglobulin G (IgG) concentrations for beef calves are limited.
objectivesTo evaluate test performance of digital (DSTP) and optical (OSTP) serum total protein (STP) refractometers and a digital Brix (DBRIX) refractometer for assessment of passive immunity in beef calves. ANIMALS: A total of 398 beef calves from 6 herds, 1 to 7 days of age.
methodsSerum IgG concentration was estimated by DSTP, OSTP, and DBRIX, and measured by radial immunodiffusion (RID). Correlation coefficients (r) among results were calculated. Optimal STP and Brix thresholds for identification of IgG <10, <16, and <24 g/L were determined using interval likelihood ratios. Refractometer performance and agreement were assessed using areas under the curve (AUC), diagnostic test characteristics, Cohen's kappa (κ), and Bland-Altman analysis.
resultsRefractometer results were highly correlated with RID (r = 0.82-0.91) and with each other (r = 0.91-0.95), and overall test performance was excellent (AUC = 0.93-0.99). The STP concentrations of ≤5.1, ≤5.1, and ≤5.7 g/dL and Brix percentages of ≤7.9%, ≤8.3%, and ≤8.7% indicated IgG concentrations <10, <16, and <24 g/L, respectively. Agreement of refractometers with RID was variable (κ = 0.46-0.80) and among refractometers was substantial (κ = 0.62-0.89). CONCLUSIONS AND CLINICAL IMPORTANCE: All refractometers showed good utility as monitoring tools for assessment of TPI in beef calves.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.