Evidence map›Paper›PMID 33368039›Full record

ArticleDoklady. Biochemistry and biophysics2020

Adaptation of Mycoplasmas to Antimicrobial Peptides: Development of Melittin Resistance in Acholeplasma laidlawii Is Associated with Changes in Genomic and Proteomic Profiles and in Virulence.

V M Chernov, N B Baranova, A A Mouzykantov, E S Medvedeva, M A Dramchini, O A Chernova

Abstract read
PubMed Publisher
In one paragraph

Article in Doklady. Biochemistry and biophysics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 84% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

V M ChernovKazan Institute of Biochemistry and Biophysics, Federal Research Center Kazan Science Center of the Russian Academy of Sciences, Kazan, Russia.
N B BaranovaKazan Institute of Biochemistry and Biophysics, Federal Research Center Kazan Science Center of the Russian Academy of Sciences, Kazan, Russia. natalja-b@yandex.ru.
A A MouzykantovKazan Institute of Biochemistry and Biophysics, Federal Research Center Kazan Science Center of the Russian Academy of Sciences, Kazan, Russia.
E S MedvedevaKazan Institute of Biochemistry and Biophysics, Federal Research Center Kazan Science Center of the Russian Academy of Sciences, Kazan, Russia.
M A DramchiniKazan (Volga Region) Federal University, Kazan, Russia.
O A ChernovaKazan Institute of Biochemistry and Biophysics, Federal Research Center Kazan Science Center of the Russian Academy of Sciences, Kazan, Russia.
Kazan Institute of Biochemistry and Biophysics · RUKazan Federal University · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

For the first time it is shown that the development of resistance to melittin in Acholeplasma laidlawii, a mycoplasma that is widely spread in nature and that is the main contaminant of cell cultures and vaccines, is associated with significant changes in the genomic profile, in cellular and vesicular proteomes, as well as in virulence.

Indexed as

Acholeplasma laidlawiiAdaptation, PhysiologicalDrug Resistance, BacterialGenome, BacterialMelittenPore Forming Cytotoxic ProteinsProteomeVirulenceMelittenPore Forming Cytotoxic ProteinsProteomeAcholeplasma laidlawiiantimicrobial peptidescellular and vesicular proteomesgenomic profilemelittinresistancevirulome

Identifiers

PMID33368039
OpenAlexW3116309912

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.