Evidence map›Paper›PMID 33367969›Full record

ArticleBiotechnology letters2021

Low-quality animal by-product streams for the production of PHA-biopolymers: fats, fat/protein-emulsions and materials with high ash content as low-cost feedstocks.

Victoria Saad, Björn Gutschmann, Thomas Grimm, Torsten Widmer, Peter Neubauer, Sebastian L Riedel

Abstract read
In one paragraph

Article in Biotechnology letters, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Polyhydroxyalkanoate production from food residues.Applied microbiology and biotechnology · 2025
    Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Tailoring the HHx monomer content of P(HB-Frontiers in bioengineering and biotechnology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Victoria Saad *Chair of Bioprocess Engineering, Institute of Biotechnology, Technische Universität Berlin, Berlin, Germany.
Björn Gutschmann *Chair of Bioprocess Engineering, Institute of Biotechnology, Technische Universität Berlin, Berlin, Germany.
Thomas GrimmANiMOX GmbH, Berlin, Germany.
Torsten WidmerANiMOX GmbH, Berlin, Germany.
Peter NeubauerChair of Bioprocess Engineering, Institute of Biotechnology, Technische Universität Berlin, Berlin, Germany.
Sebastian L RiedelChair of Bioprocess Engineering, Institute of Biotechnology, Technische Universität Berlin, Berlin, Germany. riedel@tu-berlin.de.ORCID http://orcid.org/0000-0003-1373-417X

Funding

Bundesministerium für Bildung und Forschung 031B0798ABundesministerium für Bildung und Forschung 031B0798C
6 · The paper itself

Abstract

objectiveThe rapid accumulation of crude-oil based plastics in the environment is posing a fundamental threat to the future of mankind. The biodegradable and bio-based polyhydroxyalkanoates (PHAs) can replace conventional plastics, however, their current production costs are not competitive and therefore prohibiting PHAs from fulfilling their potential.

resultsDifferent low-quality animal by-products, which were separated by thermal hydrolysis into a fat-, fat/protein-emulsion- and mineral-fat-mixture- (material with high ash content) phase, were successfully screened as carbon sources for the production of PHA. Thereby, Ralstonia eutropha Re2058/pCB113 accumulated the short- and medium-chain-length copolymer poly(hydroxybutyrate-co-hydroxyhexanoate) [P(HB-co-HHx)]. Up to 90 wt% PHA per cell dry weight with HHx-contents of 12-26 mol% were produced in shake flask cultivations.

conclusionIn future, the PHA production cost could be lowered by using the described animal by-product streams as feedstock.

Indexed as

Culture MediaFatsPolyhydroxyalkanoatesProteinsAnimalsBioreactorsCattleCupriavidus necatorEmulsionsFood IndustryIndustrial WasteMeatMetabolic EngineeringCulture MediaEmulsionsFatsIndustrial WastePolyhydroxyalkanoatesProteinsAnimal by-productsFat/protein-emulsionLow-cost feedstocksMedium-chain-length PHAP(HB-co-HHx)Ralstonia eutropha

Identifiers

PMID33367969
PMCPMC7873092

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.