Evidence map›Paper›PMID 33367960›Full record

SynthesisJournal of neurovirology2021

Meningoencephalitis associated with COVID-19: a systematic review.

Ritwick Mondal, Upasana Ganguly, Shramana Deb, Gourav Shome, Subhasish Pramanik, Deebya Bandyopadhyay, Durjoy Lahiri

Abstract readSystematic Review
In one paragraph

Synthesis in Journal of neurovirology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Observational
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Review
  14. Article
  15. Emerging Knowledge of the Neurobiology of COVID-19.The Psychiatric clinics of North America · 2022
    Review
  16. Central nervous system outcomes of COVID-19.Translational research : the journal of laboratory and clinical medicine · 2022
    Review
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ritwick MondalBangur Institute of Neurosciences, Institute of Post Graduate Medical Education and Research, SSKM Hospital, Kolkata, India.
Upasana GangulyBangur Institute of Neurosciences, Institute of Post Graduate Medical Education and Research, SSKM Hospital, Kolkata, India.
Shramana DebS.N. Pradhan Centre for Neuroscience, University of Calcutta, Kolkata, India.
Gourav ShomeDepartment of Microbiology, University of Calcutta, Kolkata, India.
Subhasish PramanikBangur Institute of Neurosciences, Institute of Post Graduate Medical Education and Research, SSKM Hospital, Kolkata, India.
Deebya BandyopadhyayBangur Institute of Neurosciences, Institute of Post Graduate Medical Education and Research, SSKM Hospital, Kolkata, India.
Durjoy LahiriBangur Institute of Neurosciences, Institute of Post Graduate Medical Education and Research, SSKM Hospital, Kolkata, India. dlahiri1988@gmail.com.ORCID http://orcid.org/0000-0002-2487-9537

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With the growing number of COVID-19 cases in recent times. significant set of patients with extra pulmonary symptoms has been reported worldwide. Here we venture out to summarize the clinical profile, investigations, and radiological findings among patients with SARS-CoV-2-associated meningoencephalitis in the form of a systemic review. This review was carried out based on the existing PRISMA (Preferred Report for Systematic Review and Meta analyses) consensus statement. The data for this review was collected from four databases: Pubmed/Medline, NIH Litcovid, Embase, and Cochrane library and Preprint servers up till 30 June 2020. Search strategy comprised of a range of keywords from relevant medical subject headings which includes "SARS-COV-2," "COVID-19," and "meningoencephalitis." All peer reviewed, case-control, case report, pre print articles satisfying our inclusion criteria were involved in the study. Quantitative data was expressed in mean ± SD, while the qualitative date in percentages. Paired t test was used for analysing the data based on differences between mean and respective values with a p < 0.05 considered to be statistically significant. A total of 61 cases were included from 25 studies after screening from databases and preprint servers, out of which 54 of them had completed investigation profile and were included in the final analysis. Clinical, laboratory findings, neuroimaging abnormalities, and EEG findings were analyzed in detail. This present review summarizes the available evidences related to the occurrence of meningoencephalitis in COVID-19.

Indexed as

AdultAgedAntiviral AgentsAzithromycinConfusionCoughCOVID-19COVID-19 Drug TreatmentDyspneaElectroencephalographyFatigueFemaleFeverHumansHydroxychloroquineMaleAntiviral AgentsAzithromycinHydroxychloroquineClinical symptomsCoronavirusCOVID-19MeningoencephalitisNeurological impairmentsSARS-CoV-2

Identifiers

PMID33367960
PMCPMC7765701

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.