ArticleJournal of neurology2021
Measuring optokinetic after-nystagmus: potential for detecting patients with signs of visual dependence following concussion.
Article in Journal of neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
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Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.
- Systematic review and meta-analysis of the diagnostic value of optokinetic after-nystagmus in vestibular disorders.Frontiers in neurology · 2024Pooled it
- Clinical characteristics of visual motion hypersensitivity: a systematic review.Experimental brain research · 2023Pooled it
- Analysis of the application of computerized optokinetic nystagmus analyzer in vision examination.BMC ophthalmology · 2026Article
- A Diagnostic Framework for the Management of Post-Concussion Visually Induced Dizziness: Recognising Postural and Visuoperceptual Subtypes Using an Optokinetic Balance Assessment.Brain sciences · 2026Article
- Temporal visual processing deficits in post concussion syndrome.Scientific reports · 2025Article
- Dutch translation and validation of the Visual Vertigo Analogue Scale (VVAS).European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025Article
- Feasibility of virtual reality to induce and measure optokinetic after-nystagmus (OKAN): a pilot study.Scientific reports · 2025Article
- Temporal dynamics of ocular torsion and vertical vergence during visual, vestibular, and visuovestibular rotations.Experimental brain research · 2024Article
- A Proposed Mechanism for Visual Vertigo: Post-Concussion Patients Have Higher Gain From Visual Input Into Subcortical Gaze Stabilization.Investigative ophthalmology & visual science · 2024Article
- Precision Concussion Management: Approaches to Quantifying Head Injury Severity and Recovery.Brain sciences · 2023Review
- Concussed patients with visually induced dizziness exhibit increased ocular torsion and vertical vergence during optokinetic gaze-stabilization.Scientific reports · 2023Article
- Patterns of vestibular dysfunction in chronic traumatic brain injury.Frontiers in neurology · 2022Article
- Alertness and Visual Attention Impact Different Aspects of the Optokinetic Reflex.Investigative ophthalmology & visual science · 2021Article
- Effect of the Stimulus Duration on the Adaptation of the Optokinetic Afternystagmus.Frontiers in neurology · 2021Article
- Psychometric Properties of Vestibular and Ocular Measures Used for Concussion Assessments: A Scoping Review.The Journal of head trauma rehabilitationArticle
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Concussed patients with chronic symptoms commonly report dizziness during exposure to environments with complex visual stimuli (e.g. supermarket aisles, busy crossroads). Such visual induced dizziness is well-known in patients with vestibular deficits, in whom it indicates an overreliance on visual cues in sensory integration. Considering that optokinetic after-nystagmus (OKAN) reflects the response of the central network integrating visual and vestibular self-motion signals (velocity storage network), we investigated OKAN in 71 patients [17 (23.9%) females, 30.36 ± 9.05 years old] who suffered from persistent symptoms after a concussion and presented clinical signs suggesting visual dependence. Data were retrospectively compared with 21 healthy individuals [13 (61.9%) females, 26.29 ± 10.00 years old]. The median values of the slow cumulative eye position and of the time constant of OKAN were significantly higher in patients than in healthy individuals (slow cumulative eye position: 124.15 ± 55.61° in patients and 77.87 ± 45.63° in healthy individuals-p = 0.012; time constant: 25.17 ± 10.27 s in patients and 13.95 ± 4.92 s in healthy individuals-p = 0.003). The receiving operating curve (ROC) estimated on the time constant had an overall area under the curve of 0.73. Analysis of the ROC suggests that a test measuring the OKAN time constant could obtain a sensitivity of 0.73 and specificity of 0.72 in determining the origin of the visual-related disturbances in those patients (threshold 16.6 s). In a subset of 43 patients who also performed the Sensory Organization Test (SOT), the proposed OKAN test was twice as sensitive as the SOT. This study suggests that concussed patients with persisting visual symptoms may have an underlying impairment of the velocity storage mechanism and that measuring the OKAN time constant can objectify such impairment.
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