Evidence map›Paper›PMID 33367727›Full record

ArticleThe Journal of antimicrobial chemotherapy2021

Re-evaluation of a novel resistance mutation in eccC5 of the ESX-5 secretion system in ofloxacin-resistant Mycobacterium tuberculosis.

Amondrea Blackman, Bob Morrison, Fernanda Maruri, Yuri van der Heijden, Cindy Hager Nochowicz, Yan Guo, Matthew Scholz, Tige Rustad, David R Sherman, Timothy R Sterling

Open access · greenAbstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of antimicrobial chemotherapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.0field-weighted citation impact, top 57% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Amondrea BlackmanDivision of Infectious Diseases, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA.
Bob MorrisonSeattle Children's Hospital, Seattle, WA, USA.
Fernanda MaruriDivision of Infectious Diseases, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA.
Yuri van der HeijdenDivision of Infectious Diseases, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA.
Cindy Hager NochowiczDivision of Infectious Diseases, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA.
Yan GuoUniversity of New Mexico, Albuquerque, NM, USA.
Matthew ScholzVanderbilt Technologies for Advanced Genomics (VANTAGE) Core, Vanderbilt University Medical Center, Nashville, TN, USA.
Tige RustadSeattle Children's Hospital, Seattle, WA, USA.
David R ShermanSeattle Children's Hospital, Seattle, WA, USA.
Timothy R SterlingDivision of Infectious Diseases, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA.
Vanderbilt University · USSeattle Children's Hospital · USAurum Institute · ZAUniversity of New Mexico · USVanderbilt University Medical Center · US

Funding

Fluoroquinolone Resistance in M. TuberculosisR01AI063200 · NIAID · VANDERBILT UNIVERSITY · PI STERLING, TIMOTHY R · 2006 to 2010
$1.8M
Fluoroquinolone resistance in patients with multidrug-resistant tuberculosisK08AI106420 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI VAN DER HEIJDEN, YURI F. · 2014 to 2018
$848k
Fluoroquinolones and Efflux-Mediated Cross Resistance in HIV-related TBR56AI118361 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI SHERMAN, DAVID R, STERLING, TIMOTHY R · 2016 to 2016
$696k
NIAID NIH HHS K08 AI106420NIAID NIH HHS R01 AI063200NIAID NIH HHS R56 AI118361
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Bacterial ProteinsMycobacterium tuberculosisType VII Secretion SystemsDrug Resistance, BacterialMutationOfloxacinBacterial ProteinsOfloxacinType VII Secretion Systems

Identifiers

PMID33367727
PMCPMC7879138
OpenAlexW3117395557

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.