Evidence map›Paper›PMID 33367670›Full record

ArticleJournal of the American Medical Informatics Association : JAMIA2021

Artificial intelligence in breast cancer screening: primary care provider preferences.

Nathaniel Hendrix, Brett Hauber, Christoph I Lee, Aasthaa Bansal, David L Veenstra

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Medical Informatics Association : JAMIA, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 7 pooled it
3.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 7 syntheses or guidelines pooled it, 50 citations in OpenAlex.

  1. Pooled it
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  10. Article
  11. Review
  12. AI and Primary Care: Scoping Review.Journal of medical Internet research · 2025
    Article
  13. Article
  14. Article
  15. Artificial Intelligence in Radiology: A Leadership Survey.Journal of the American College of Radiology : JACR · 2025
    Article
  16. Article
  17. Article
  18. Review
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Nathaniel HendrixThe Comparative Health Outcomes, Policy & Economics (CHOICE) Institute, University of Washington School of Pharmacy, Seattle, Washington, USA.ORCID 0000-0001-8154-0276
Brett HauberThe Comparative Health Outcomes, Policy & Economics (CHOICE) Institute, University of Washington School of Pharmacy, Seattle, Washington, USA.
Christoph I LeeDepartment of Radiology, University of Washington School of Medicine, Seattle, Washington, USA.
Aasthaa BansalThe Comparative Health Outcomes, Policy & Economics (CHOICE) Institute, University of Washington School of Pharmacy, Seattle, Washington, USA.
David L VeenstraThe Comparative Health Outcomes, Policy & Economics (CHOICE) Institute, University of Washington School of Pharmacy, Seattle, Washington, USA.
University of Washington · US

Funding

Transform Dissemination and Implementation Science in CTSA ProgramsUL1TR002319 · NCATS · UNIVERSITY OF WASHINGTON · PI John K. Amory · 2017 to 2026
$100.0M
NCCIH Supplement to NCATS/CTSA Program for KL2 Scholars - M. SoddersKL2TR002317 · NCATS · UNIVERSITY OF WASHINGTON · PI Christy Michelle McKinney · 2017 to 2026
$14.5M
Developing Data-Driven Cancer ResearchersT32CA009168 · NCI · UNIVERSITY OF WASHINGTON · PI STEPHEN M SCHWARTZ, MICHAEL Chiao-An WU · 1985 to 2026
$10.1M
NRSA Training CoreTL1TR002318 · NCATS · UNIVERSITY OF WASHINGTON · PI Megan Moore · 2017 to 2026
$8.4M
Artificial Intelligence for Improved Breast Cancer Screening Accuracy: External Validation, Refinement, and Clinical TranslationR37CA240403 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI CHRISTOPH I LEE · 2020 to 2026
$3.8M
NCATS NIH HHS KL2 TR002317NCATS NIH HHS TL1 TR002318NCATS NIH HHS UL1 TR002319NCI NIH HHS R37 CA240403NCI NIH HHS T32 CA009168
6 · The paper itself

Abstract

backgroundArtificial intelligence (AI) is increasingly being proposed for use in medicine, including breast cancer screening (BCS). Little is known, however, about referring primary care providers' (PCPs') preferences for this technology.

methodsWe identified the most important attributes of AI BCS for ordering PCPs using qualitative interviews: sensitivity, specificity, radiologist involvement, understandability of AI decision-making, supporting evidence, and diversity of training data. We invited US-based PCPs to participate in an internet-based experiment designed to force participants to trade off among the attributes of hypothetical AI BCS products. Responses were analyzed with random parameters logit and latent class models to assess how different attributes affect the choice to recommend AI-enhanced screening.

resultsNinety-one PCPs participated. Sensitivity was most important, and most PCPs viewed radiologist participation in mammography interpretation as important. Other important attributes were specificity, understandability of AI decision-making, and diversity of data. We identified 3 classes of respondents: "Sensitivity First" (41%) found sensitivity to be more than twice as important as other attributes; "Against AI Autonomy" (24%) wanted radiologists to confirm every image; "Uncertain Trade-Offs" (35%) viewed most attributes as having similar importance. A majority (76%) accepted the use of AI in a "triage" role that would allow it to filter out likely negatives without radiologist confirmation. CONCLUSIONS AND RELEVANCE: Sensitivity was the most important attribute overall, but other key attributes should be addressed to produce clinically acceptable products. We also found that most PCPs accept the use of AI to make determinations about likely negative mammograms without radiologist confirmation.

Indexed as

Artificial IntelligenceAttitude of Health PersonnelPhysicians, Primary CareRadiographic Image Interpretation, Computer-AssistedAttitude to ComputersBreast NeoplasmsEarly Detection of CancerFemaleHumansMammographyPrimary Health CareSensitivity and SpecificityUnited Statesartificial intelligencebreast cancer screeningconjoint analysisdiscrete choiceprimary care

Identifiers

PMID33367670
PMCPMC8200265
OpenAlexW3116297975

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.