ArticleThe journal of nutrition, health & aging2021
Effects of Comorbidities on the Elderly Patients with COVID-19: Clinical Characteristics of Elderly Patients Infected with COVID-19 from Sichuan, China.
Article in The journal of nutrition, health & aging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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15 citing papers in PubMed, 38 citations in OpenAlex.
- Prevalence and factors associated with fear of COVID-19 in military personnel during the second epidemic wave in Peru.Frontiers in psychiatry · 2024Article
- Efficacy and safety of Paxlovid in severe adult patients with SARS-Cov-2 infection: a multicenter randomized controlled study.The Lancet regional health. Western Pacific · 2023Article
- Biological sex and age-related differences shape the antiviral response to SARS-CoV-2 infection.Heliyon · 2023Article
- Extraordinary Impacts on the Healthcare Workforce:: COVID-19 and Aging.Delaware journal of public health · 2022Article
- Cardiovascular, Pulmonary, and Neuropsychiatric Short- and Long-Term Complications of COVID-19.Cells · 2022Review
- Article
- Heterogeneity and Risk of Bias in Studies Examining Risk Factors for Severe Illness and Death in COVID-19: A Systematic Review and Meta-Analysis.Pathogens (Basel, Switzerland) · 2022Review
- COVID-19 mortality and its predictors in the elderly: A systematic review.Health science reports · 2022Review
- Editorial: Journal of Nutrition, Health and Aging: Summary of Recent Work and Future Directions.The journal of nutrition, health & aging · 2022Article
- Evaluation of the Health Situation among Recovered Cases of COVID-19 in West Bank, Palestine, and Their Onset/Recovery Time.Journal of environmental and public health · 2022Article
- COVID-19 fatalities by zip codes and socioeconomic indicators across various U.S. regions.Annals of medicine and surgery (2012) · 2021Article
- Review
- Clinical Characteristics and Short-Term Outcomes of Acute Kidney Injury Missed Diagnosis in Older Patients with Severe COVID-19 in Intensive Care Unit.The journal of nutrition, health & aging · 2021Article
- Investigation of a COVID-19 Outbreak and Its Successful Containment in a Long Term Care Facility in Qatar.Frontiers in public health · 2021Article
- Follow-Up Study of the Cardiopulmonary and Psychological Outcomes of COVID-19 Survivors Six Months After Discharge in Sichuan, China.International journal of general medicine · 2021Article
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe co-occurrence of chronic diseases in the elderly is a common problem. However, the relationship between comorbidities and the prognosis of elderly patients with COVID-19 was not clear. This study was supposed to describe the clinical characteristics of elderly patients with COVID-19 infection from Sichuan province and the effects of comorbidity.
designA retrospective study. SETTINGS AND
participantsCOVID-19 patients from Public Health Clinical Center of Chengdu between December 16, 2019 and February 26, 2020 were included in this study. Patients were divided into elderly group (≥60 years old) and non-elderly group (< 60 years old).
resultsElderly patients with COVID-19 indicated relatively higher proportion of comorbidities, and the most common were atherosclerotic cardiovascular disease (56.5%), hypertension (43.5%) and chronic pulmonary disease (21.7%). The proportion of severe cases was higher in elderly group than that in non-elderly group (73.9% and 42.2%, respectively, P=0.012). During hospitalization, elderly patients indicated relatively higher proportion of complications, such as shock (21.7%), respiratory failure (21.7%). The proportion of patients with a decreased number of CD8+ lymphocytes (82.6%) and B lymphocytes (77.8%) in elderly patients was significantly higher than that in non-elderly group (48.9% and 44.8%, respectively). All 3 deaths were elderly patients with comorbidities and the cell counts of T lymphocyte subsets, B and NK cells of them were significantly decreased at admission.
conclusionsElderly patients with COVID-19 had a high proportion of severe cases and comorbidities, more likely to show low immune function, and indicate higher proportion of complications.
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