ArticleBJR open2020
Decreasing the radiation dose for contrast-enhanced abdominal spectral CT with a half contrast dose: a matched-pair comparison with a 120 kVp protocol.
Article in BJR open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Optimization of hypovascular liver lesion detectability in dual-energy CT using deep learning image reconstruction: a phantom study for potential iodine dose reduction.European radiology experimental · 2026Article
- Photon-counting versus energy-integrating CT of abdomen-pelvis: a phantom study on the potential for reducing iodine contrast media.European radiology experimental · 2025Article
- Size-Specific Dose Estimate and Effective Dose for Pediatric Computed Tomography.Journal of medical physicsArticle
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo compare the estimated radiation dose of 50% reduced iodine contrast medium (halfCM) for virtual monochromatic images (VMIs) with that of standard CM (stdCM) with a 120 kVp imaging protocol for contrast-enhanced CT (CECT).
methodsWe enrolled 30 adults with renal dysfunction who underwent abdominal CT with halfCM for spectral CT. As controls, 30 matched patients without renal dysfunction using stdCM were also enrolled. CT images were reconstructed with the VMIs at 55 keV with halfCM and 120 kVp images with stdCM and halfCM. The Monte-Carlo simulation tool was used to simulate the radiation dose. The organ doses were normalized to CTDIvol for the liver, pancreas, spleen, and kidneys and measured between halfCM and stdCM protocols.
resultsFor the arterial phase, the mean organ doses normalized to CTDIvol for stdCM and halfCM were 1.22 and 1.29 for the liver, 1.50 and 1.35 for the spleen, 1.75 and 1.51 for the pancreas, and 1.89 and 1.53 for the kidneys. As compared with non-enhanced CT, the average increase in the organ dose was significantly lower for halfCM (13.8% ± 14.3 and 26.7% ± 16.7) than for stdCM (31.0% ± 14.3 and 38.5% ± 14.8) during the hepatic arterial and portal venous phases (
conclusionAs compared with stdCM with the 120 kVp imaging protocol, a 50% reduction in CM with VMIs with the 55 keV protocol allowed for a substantial reduction of the average organ dose of iodine CM while maintaining the iodine CT number for CECT. ADVANCES IN KNOWLEDGE: This study provides that the halfCM protocol for abdominal CT with a dual-layer-dual-energy CT can significantly reduce the increase in the average organ dose for non-enhanced CT as compared with the standard CM protocol.
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