Evidence map›Paper›PMID 33365393›Full record

ArticleLaryngoscope investigative otolaryngology2020

Olfactory and taste dysfunction among mild-to-moderate symptomatic COVID-19 positive health care workers: An international survey.

Peter J Andrews, Alfonso Luca Pendolino, Giancarlo Ottaviano, Bruno Scarpa, Joseph Grant, Piergiorgio Gaudioso, Anna Bordin, Rosario Marchese-Ragona, Davide Leoni, Annamaria Cattelan and 5 more

Open access · goldAbstract read
In one paragraph

Article in Laryngoscope investigative otolaryngology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 3 pooled it
2.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 3 syntheses or guidelines pooled it, 39 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Classical and Speech Therapy Olfactory Training in the Treatment of COVID-19-Related Olfactory Disorders.Medical science monitor : international medical journal of experimental and clinical research · 2026
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  11. COVID-19 Oral Sequelae: Persistent Gustatory and Saliva Secretory Dysfunctions after Recovery from COVID-19.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 2 countries.

Peter J AndrewsDepartment of Ear, Nose and Throat Royal National ENT & Eastman Dental Hospitals London UK.ORCID https://orcid.org/0000-0001-5731-3276
Alfonso Luca PendolinoDepartment of Ear, Nose and Throat Royal National ENT & Eastman Dental Hospitals London UK.ORCID https://orcid.org/0000-0002-6348-5303
Giancarlo OttavianoDepartment of Neurosciences, Otolaryngology Section University of Padova Padova Italy.ORCID https://orcid.org/0000-0003-2433-4761
Bruno ScarpaDepartment of Statistical Sciences and Department of Mathematics Tullio Levi-Civita University of Padova Padova Italy.
Joseph GrantDepartment of Microbiology Whittington Health London UK.
Piergiorgio GaudiosoDepartment of Neurosciences, Otolaryngology Section University of Padova Padova Italy.
Anna BordinDepartment of Neurosciences, Otolaryngology Section University of Padova Padova Italy.
Rosario Marchese-RagonaDepartment of Neurosciences, Otolaryngology Section University of Padova Padova Italy.
Davide LeoniUnit of Infectious Disease University Hospital of Padova Padova Italy.
Annamaria CattelanUnit of Infectious Disease University Hospital of Padova Padova Italy.
Anika KauraDepartment of Ear, Nose and Throat Royal National ENT & Eastman Dental Hospitals London UK.ORCID https://orcid.org/0000-0003-3563-5164
Simon GaneDepartment of Ear, Nose and Throat Royal National ENT & Eastman Dental Hospitals London UK.
Nick J HamiltonDepartment of Ear, Nose and Throat Royal National ENT & Eastman Dental Hospitals London UK.
David ChoiInstitute of Neurology University College London London UK.
Julie A AndrewsDepartment of Microbiology Whittington Health London UK.
University of Padua · ITRoyal National Throat Nose and Ear Hospital · GBWhittington Health NHS Trust · GBUniversity College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo determine the prevalence of olfactory and taste dysfunction (OD; TD) among COVID-19 positive health care workers (HCWs), their associated risk factors and prognosis.

methodsBetween May and June 2020, a longitudinal multicenter study was conducted on symptomatic COVID-19 PCR confirmed HCWs (COVID-19 positive) in London and Padua.

resultsHundred and fourteen COVID-19 positive HCWs were surveyed with a response rate of 70.6% over a median follow-up period of 52 days. UK prevalence of OD and TD was 73.1% and 69.2%, respectively. There was a male to female ratio of 1:3 with 81.6% being white, 43.7% being nurses/health care assistants (HCAs), and 39.3% being doctors. In addition, 53.2% of them worked on COVID-19 wards. Complete recovery was reported in 31.8% for OD and 47.1% for TD with a 52 days follow-up. The job role of doctors and nurses negatively influenced smell (

conclusionsThe prevalence of OD and TD was considerably higher in HCWs. The prognosis for OD and TD recovery was worse for nurses/HCAs and doctors but working on a COVID-19 ward did not influence prognosis. Sixty-eight percent of surveyed HCWs at 52 days continued to experience OD or TD requiring additional future medical management capacity. LEVEL OF EVIDENCE: 4.

Indexed as

COVID‐19olfactory dysfunctionrhinologysmellsurveytastetaste dysfunction

Identifiers

PMID33365393
PMCPMC7752034
OpenAlexW3107300999

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.