Evidence map›Paper›PMID 33365351›Full record

ArticleACG case reports journal2020

Graft-vs-Host Disease After Liver Transplantation: A Diagnostic and Management Challenge.

Jerry Yung-Lun Chin, Jiayi Gong, Edward Gane

Open access · diamondAbstract readCase Reports
In one paragraph

Article in ACG case reports journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jerry Yung-Lun ChinNew Zealand Liver Transplant Unit (NZLTU), Auckland City Hospital, Auckland, New Zealand.
Jiayi GongDepartement of Pharmacy, Auckland City Hospital, Auckland, New Zealand.
Edward GaneNew Zealand Liver Transplant Unit (NZLTU), Auckland City Hospital, Auckland, New Zealand.
Auckland City Hospital · NZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 65-year-old White man underwent deceased donor liver transplant for decompensated liver cirrhosis secondary to alpha-1-antitrypsin deficiency. He developed diarrhea and diffuse maculopapular rash 2 months post-transplant. Skin biopsy revealed necroinflammatory changes related to the superficial dermis. Pancytopenia ensued, complicated by neutropenic sepsis. Chimerism studies confirmed the presence of donor T-lymphocyte macrochimerism (63%). The patient was diagnosed with graft-vs-host disease. After extensive multidisciplinary collaboration, basiliximab was initiated. This resulted in complete symptom resolution and a gradual reduction in T-lymphocyte macrochimerism (12%). The patient was later transitioned to oral ruxolitinib and currently remains in stable condition 16 months after being diagnosed with graft-vs-host disease.

Identifiers

PMID33365351
PMCPMC7752685
OpenAlexW3115407690

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.