Evidence map›Paper›PMID 33365190›Full record

ArticleSurgical neurology international2020

Bilateral occipital metastases: Visual deficits and management considerations.

Mark M Zaki, Saksham Gupta, Blake Hauser, Kyle C Wu, Robert M Mallery, Sashank Prasad, Ayal Aizer, Wenya Linda Bi, Ian F Dunn

Open access · hybridAbstract read
In one paragraph

Article in Surgical neurology international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Mark M ZakiDepartment of Neurosurgery, Brigham and Women's Hospital, Dana-Farber Cancer Institute, Boston, Massachusetts United States.
Saksham GuptaDepartment of Neurosurgery, Brigham and Women's Hospital, Dana-Farber Cancer Institute, Boston, Massachusetts United States.
Blake HauserDepartment of Neurosurgery, Brigham and Women's Hospital, Dana-Farber Cancer Institute, Boston, Massachusetts United States.
Kyle C WuDepartment of Neurosurgery, Brigham and Women's Hospital, Dana-Farber Cancer Institute, Boston, Massachusetts United States.
Robert M MalleryDepartment of Neurology, Brigham and Women's Hospital, Dana-Farber Cancer Institute, Boston, Massachusetts United States.
Sashank PrasadDepartment of Neurology, Brigham and Women's Hospital, Dana-Farber Cancer Institute, Boston, Massachusetts United States.
Ayal AizerDepartment of Radiation Oncology, Brigham and Women's Hospital, Dana-Farber Cancer Institute, Boston, Massachusetts, United States.
Wenya Linda BiDepartment of Neurosurgery, Brigham and Women's Hospital, Dana-Farber Cancer Institute, Boston, Massachusetts United States.
Ian F DunnDepartment of Neurosurgery, University of Oklahoma Health Sciences Center, Oklahoma, United States.
University of Oklahoma Health Sciences Center · US

Funding

Medical Scientist Training ProgramT32GM007753 · NIGMS · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI WALENSKY, LOREN DAVID · 1985 to 2021
$50.0M
NIGMS NIH HHS T32 GM007753
6 · The paper itself

Abstract

backgroundMetastases to the bilateral occipital lobes pose a difficult clinical scenario due to risk of debilitating visual loss. We sought to characterize clinical outcomes following different treatment modalities to help guide management in this challenging situation.

methodsWe retrospectively reviewed brain metastases patients treated at a single institution between 2008 and 2017 and assessed visual symptoms before and after treatment, the tumor and peritumoral edema volumes before treatment, and clinical outcomes including mortality.

resultsEighteen patients with metastases affecting both occipital lobes were identified. Lung cancer represented the most common primary (

conclusionPatients with symptomatic bilateral occipital lobe metastases may experience visual improvement following intervention, especially if symptoms stem from compression or edema. Those without visual symptoms are at risk of developing new visual deficits during treatment, which should be included in the decision-making process and when counseling patients. Visual deficits improved after surgery in the majority of patients, with no cases of immediate visual deterioration.

Indexed as

BlindnessBrain metastasesOccipitalRadiationVision

Identifiers

PMID33365190
PMCPMC7749938
OpenAlexW3113187675

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.