Evidence map›Paper›PMID 33365145›Full record

ArticleRegenerative biomaterials2020

Design and characterization of plasticized bacterial cellulose/waterborne polyurethane composite with antibacterial function for nasal stenting.

Zhaoxuan Feng, Minglu Li, Xing Jin, Yudong Zheng, Junxiu Liu, Liang Zhao, Yansen Wang, Hao Li, Danlin Zuo

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Regenerative biomaterials, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Zhaoxuan FengSchool of Material Science and Engineering, University of Science and Technology Beijing, Beijing, China.
Minglu LiSchool of Material Science and Engineering, University of Science and Technology Beijing, Beijing, China.
Xing JinDepartment of Otorhinolaryngology, Peking University Third Hospital, Beijing, China.
Yudong ZhengSchool of Material Science and Engineering, University of Science and Technology Beijing, Beijing, China.
Junxiu LiuDepartment of Otorhinolaryngology, Peking University Third Hospital, Beijing, China.
Liang ZhaoResearch Center for Bioengineering and Sensing Technology, University of Science and Technology Beijing, Beijing 100083, China.
Yansen WangSchool of Material Science and Engineering, University of Science and Technology Beijing, Beijing, China.
Hao LiSchool of Material Science and Engineering, University of Science and Technology Beijing, Beijing, China.
Danlin ZuoSchool of Material Science and Engineering, University of Science and Technology Beijing, Beijing, China.
University of Science and Technology Beijing · CNPeking University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A nasal stent capable of preventing adhesions and inflammation is of great value in treating nasal diseases. In order to solve the problems of tissue adhesion and inflammation response, we prepared plasticized bacterial cellulose (BCG) and waterborne polyurethane (WPU) composite with antibacterial function used as a novel nasal stent. The gelation behavior of BCG could contribute to protecting the paranasal sinus mucosa; meanwhile, the WPU with improved mechanical property was aimed at supporting the narrow nasal cavity. The thickness, size and the supporting force of the nasal stent could be adjusted according to the specific conditions of the nasal. Thermogravimetric analysis, contact angle and water absorption test were applied to investigate the thermal, hydrophilic and water absorption properties of the composite materials. The composite materials loaded with poly(hexamethylene biguanide) hydrochloride maintained well antibacterial activity over 12 days. Animal experiments further revealed that the mucosal epithelium mucosae damage of BCG-WPU composite was minor compared with that of WPU. This new type of drug-loaded nasal stent can effectively address the postoperative adhesions and infections while ensuring the health of nasal mucosal, and thus has an immense clinical application prospects in treating nasal diseases.

Indexed as

bacterial cellulosebiocompatibilitynasal stentpolyurethane

Identifiers

PMID33365145
PMCPMC7748449
OpenAlexW3117361042

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.