Evidence map›Paper›PMID 33364933›Full record

ArticleFrontiers in aging neuroscience2020

The Future of GDNF in Parkinson's Disease.

Fredric P Manfredsson, Nicole K Polinski, Thyagarajan Subramanian, Nicholas Boulis, Dustin R Wakeman, Ronald J Mandel

Open access · goldAbstract read
In one paragraph

Article in Frontiers in aging neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 49 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Disease-modifying, multidimensional efficacy of putaminal CaMolecular therapy : the journal of the American Society of Gene Therapy · 2025
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Assessment of CRISPRa-mediatedFrontiers in bioengineering and biotechnology · 2024
    Article
  14. Review
  15. Downregulation of striatal CaNeurobiology of disease · 2023
    Article
  16. Article
  17. Review
  18. Review
  19. Review
  20. Parkinson's Disease: A Tale of Many Players.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 6 institutions in 1 country.

Fredric P ManfredssonDepartment of Neurobiology, Barrow Neurological Institute, Phoenix, AZ, United States.
Nicole K PolinskiThe Michael J. Fox Foundation for Parkinson's Research, New York, NY, United States.
Thyagarajan SubramanianDepartment of Neurology and Neural and Behavioral Sciences, Penn State University College of Medicine, Hershey, PA, United States.
Nicholas BoulisDepartment of Neurosurgery, Emory University, Atlanta, GA, United States.
Dustin R WakemanVirscio, Inc., New Haven, CT, United States.
Ronald J MandelDepartment of Neuroscience, University of Florida, Gainesville, FL, United States.
Barrow Neurological Institute · USEmory University · USMichael J. Fox Foundation · USPennsylvania State University · USUniversity of Florida · USVirscio (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

clinical trial (2.172)GDNF (glial cell line-derived neurotrophic factor)gene therapy (GT)neurotrophic factorneurturinParkinson's disease

Identifiers

PMID33364933
PMCPMC7750181
OpenAlexW3110940321

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.