ArticleFrontiers in cellular neuroscience2020
Brain Temperature Alters Contributions of Excitatory and Inhibitory Inputs to Evoked Field Potentials in the Rat Frontal Cortex.
Article in Frontiers in cellular neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 16 citations in OpenAlex.
- Miniaturized Bidirectional Thermal Stimulation System Integrated With an Electrode Array for Recording Neural Activities.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Genetic inactivation of TRPM4 does not alter the temperature-dependent movement of mouse microglia.The journal of physiological sciences : JPS · 2026Article
- Early Dynamics of Body Temperature in Acute Stroke: Insights into Outcomes and Management.Journal of clinical medicine · 2026Article
- Beyond Seizures: A Comprehensive Review of Giant Somatosensory Evoked Potentials.Journal of clinical medicine · 2025Review
- Model-based correction of rapid thermal confounds in fluorescence neuroimaging of targeted perturbation.Neurophotonics · 2024Article
- Toward the Next Generation of Neural Iontronic Interfaces.Advanced healthcare materials · 2023Article
- Thermal safety considerations for implantable micro-coil design.Journal of neural engineering · 2023Article
- Exploring relationships between autistic traits and body temperature, circadian rhythms, and age.Scientific reports · 2023Article
- Temperature-dependent structural plasticity of hippocampal synapses.Frontiers in cellular neuroscience · 2022Article
- Preventive Administration of the Heat Shock Protein Hsp70 Relieves Endotoxemia-Induced Febrile Reaction in Pigeons (Journal of evolutionary biochemistry and physiology · 2021Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Changes in brain temperature have been reported to affect various brain functions. However, little is known about the effects of temperature on the neural activity at the network level, where multiple inputs are integrated. In this study, we recorded cortical evoked potentials while altering the local brain temperature in anesthetized rats. We delivered electrical stimulations to the midbrain dopamine area and measured the evoked potentials in the frontal cortex, the temperature of which was locally altered using a thermal control device. We focused on the maximum negative peaks, which was presumed to result mainly from polysynaptic responses, to examine the effect of local temperature on network activity. We showed that focal cortical cooling increased the amplitude of evoked potentials (negative correlation, >17°C); further cooling decreased their amplitude. This relationship would be graphically represented as an inverted-U-shaped curve. The pharmacological blockade of GABAergic inhibitory inputs eliminated the negative correlation (>17°C) and even showed a positive correlation when the concentration of GABA
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.