ArticleJournal of experimental pharmacology2020
Evaluation of Diuretic Activity and Phytochemical Contents of Aqueous Extract of the Shoot Apex of
Article in Journal of experimental pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 25 citations in OpenAlex.
- In Vivo Diuretic Efficacy, Antioxidant Capacity, and Mineral Profiling of Tree Gum Exudates from Sour Cherry (Pharmaceuticals (Basel, Switzerland) · 2026Article
- LC-MS/MS characterization, biological activity, and carbonic anhydrase inhibitory potential of five medicinal plant extracts from Romania and Türkiye.Scientific reports · 2026Article
- Total Phenolic and Flavonoid Contents and Antioxidant Activity ofRecent patents on biotechnology · 2026Article
- Evaluation of Diuretic Activity of Aqueous and Hydro Methanolic Crude Extracts and Solvent Fraction of the Hydromethanolic Flower Extract ofJournal of experimental pharmacology · 2024Article
- Article
- Medicinal plants utilized in the management of epilepsy in Ethiopia: ethnobotany, pharmacology and phytochemistry.Chinese medicine · 2022Review
- Naturally Occurring 8ß,13ß-kaur-15-en-17-al and Anti-Malarial Activity fromPharmaceuticals (Basel, Switzerland) · 2022Article
- Divya-Herbal-Peya Decoction Harmonizes the Inflammatory Response in Lipopolysaccharide-Induced Zebrafish Model.Journal of experimental pharmacology · 2021Article
- Unveiling Nephroprotective, Diuretic and Toxicity Response ofDose-response : a publication of International Hormesis SocietyArticle
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn Ethiopian folk medicine
objectiveTo determine the diuretic activity and phytochemical contents of the aqueous extract of the shoot apexes of
methodsThe coarse powder of
resultsThe aqueous extract induced diuresis, natriuresis, and kaliuresis in a dose- and time-dependent manner as compared to the negative control. The extract at 200 and 400 mg/kg doses produced significant diuresis (p<0.001) by the end of the fifth hour compared to the negative control. Excretion of sodium, potassium, and chloride also significantly (p<0.001) increased following extract administration. In addition, there was a significant change in the pH of urine samples of the extract-treated group compared with the negative control. Qualitative and quantitative determination of phytochemicals revealed the presence of alkaloids, flavonoids, phenolics, and tannins with the value of 128.4 mg atropine equivalents (AE)/g, 142.23 mg quercetin equivalents (QE)/g, 196.84 mg gallic acid equivalents (GAE)/g, and 25.5 mg tannic acid equivalents (TAE)/g, respectively. The aqueous extract exhibited significant diuretic activity due to its phytochemical content, which could be used as a starting point for further studies.
conclusionThe aqueous extract showed significant diuretic activity and confirmed the folkloric use of
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