Evidence map›Paper›PMID 33364622›Full record

ArticleSTAR protocols2021

Maria Mougkogianni, Argyro Kalogeropoulou, Nickolaos Nikiforos Giakoumakis, Zoi Lygerou, Stavros Taraviras

Abstract read
In one paragraph

Article in STAR protocols, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Maria MougkogianniDepartment of Physiology, School of Medicine, University of Patras, Rio, Patras 26504, Greece.
Argyro KalogeropoulouDepartment of Physiology, School of Medicine, University of Patras, Rio, Patras 26504, Greece.
Nickolaos Nikiforos GiakoumakisDepartment of Physiology, School of Medicine, University of Patras, Rio, Patras 26504, Greece.
Zoi LygerouDepartment of General Biology, School of Medicine, University of Patras, Rio, Patras 26504, Greece.
Stavros TaravirasDepartment of Physiology, School of Medicine, University of Patras, Rio, Patras 26504, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The recruitment of the minichromosome maintenance complex (MCM) on DNA replication origins is a critical process for faithful genome duplication termed licensing. Aberrant licensing has been associated with cancer and, recently, with neurodevelopmental diseases. Investigating MCM loading in complicated tissues, such as brain, remains challenging. Here, we describe an optimized approach for the qualitative and quantitative analysis of DNA-bound MCMs in the developing mouse cortex through direct imaging, offering an innovative insight into the research of origin licensing

Indexed as

DNA ReplicationAnimalsCerebral CortexDNAMiceMicroscopy, FluorescenceMinichromosome Maintenance ProteinsDNAMinichromosome Maintenance ProteinsCell BiologyMicroscopyModel OrganismsMolecular BiologyNeuroscience

Identifiers

PMID33364622
PMCPMC7753948

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.