ArticleMetabolism open2021
Hypoglycemic, antidyslipidemic and antioxydant effects of
Article in Metabolism open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 37 citations in OpenAlex.
- Article
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- Effects of Apilarnil on Type 2 Diabetes-Induced IRS-1/PI3K/Akt Mediated Insulin Resistance in Male Rats.ACS omega · 2025Article
- The Potential Effect of Dapagliflozin and Liraglutide in Attenuating Cardio-Renal Injuries in Diabetic Rats.Journal of experimental pharmacology · 2025Article
- Effects ofFrontiers in pharmacology · 2025Article
- Antidiabetic activity of the aqueous extract ofMetabolism open · 2024Article
- Antidiabetic activity ofFrontiers in pharmacology · 2023Article
- Article
- Article
- Article
- Insulin-Mimic Components inPharmaceuticals (Basel, Switzerland) · 2021Article
- Herbal Medicines Targeting the ImprovedEvidence-based complementary and alternative medicine : eCAM · 2021Review
- Evaluation of Antidiabetic Properties of the Leaves Extract ofTheScientificWorldJournal · 2021Article
- Potential use ofIndian journal of pharmacologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroud
methodsTo induce type 2 diabetes mellitus (T2DM), animals were fed a high-fat diet for 4 weeks followed by an intraperitoneal injection of 35 mg/kg of streptozotocin. Diabetic rats were divided into groups and treated for 28 days with
resultsAEVP (250 and 500 mg/kg) improved the drop in body weight, polyphagia, polydipsia and polyuria in diabetic rats. AEVP significantly reduced the concentrations of glucose, total cholesterol, triacylglycerol, urea, creatinine, activities of transaminases, and increased the levels of high density lipoprotein cholesterol and serum insulin. AEVP resulted in a decrease in malondialdehyde levels and an increase in catalase and superoxide dismutase activities. An increase in the size and number of islets in the pancreas has also been observed after administration of the extract.
conclusionAEVP has antidiabetic, antidyslipidemic and antioxidant properties, thus confirming its traditional use for the treatment of diabetes. These effects could be due to the presence of phytoconstituents, phenols and flavonoids presents in the plant extract.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.