Evidence map›Paper›PMID 33364518›Full record

ArticleAmerican journal of ophthalmology case reports2020

Bilateral optic neuritis with spine demyelination associated with influenza A H1N1 infection.

Selvakumar Ambika, Padma Lakshmi, Olma Veena Noronha

Open access · goldAbstract readCase Reports
In one paragraph

Article in American journal of ophthalmology case reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Selvakumar AmbikaDepartment of Neuro-ophthalmology, Sankara Nethralaya- A unit of Medical Research Foundation, 18 College Road, Nungambakkam, Chennai, 600 006, India.
Padma LakshmiDepartment of Neuro-ophthalmology, Sankara Nethralaya- A unit of Medical Research Foundation, 18 College Road, Nungambakkam, Chennai, 600 006, India.
Olma Veena NoronhaDepartment of Radiology, Sankara Nethralaya- A unit of Medical Research Foundation, 18 College Road, Nungambakkam, Chennai, 600 006, India.
Sankara Nethralaya · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo report a rare case of optic neuritis with spine demyelination following H1N1 virus infection. OBSERVATION: A 66-year-old female presented with decreased vision in both eyes (left > right) following a recent episode of fever and flu. She was diagnosed as H1N1 infection confirmed by viral antigen analysis of throat swab. On examination, she had a profound vision drop in the left eye with optic disc edema. MRI brain and orbit revealed bilateral optic nerve and frontal dural thickening with a ring-enhancing lesion in the right frontal lobe. MRI spine showed long cord signals at T1-T7 suggestive of demyelination. The patient had a complete recovery of vision and visual fields after intravenous and oral steroids. CONCLUSION/IMPORTANCE: Influenza A virus can manifest with a wide range of symptoms including flu-like illness to neurological complications. This case highlights optic neuritis as a presenting feature of H1N1 infection.

Indexed as

DemyelinationDisc edemaH1N1MRIOptic neuritisSteroids

Identifiers

PMID33364518
PMCPMC7750147
OpenAlexW3111001327

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.