Evidence map›Paper›PMID 33364406›Full record

ReviewLaryngoscope investigative otolaryngology2020

Does

Vishal Narwani, Alexandra Bourdillon, Keerthana Nalamada, R Peter Manes, Douglas M Hildrew

Open access · goldAbstract readReview
In one paragraph

Review in Laryngoscope investigative otolaryngology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 12 citations in OpenAlex.

  1. Cannabis use amongst tinnitus patients: consumption patterns and attitudes.Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale · 2023
    Article
  2. Article
  3. DoesLaryngoscope investigative otolaryngology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Vishal NarwaniDivision of Otolaryngology - Head and Neck Surgery, Department of Surgery Yale University School of Medicine New Haven Connecticut USA.ORCID https://orcid.org/0000-0001-8366-0255
Alexandra BourdillonYale University School of Medicine New Haven Connecticut USA.ORCID https://orcid.org/0000-0001-5111-7450
Keerthana NalamadaDepartment of Neurology University of Connecticut Farmington Connecticut USA.
R Peter ManesDivision of Otolaryngology - Head and Neck Surgery, Department of Surgery Yale University School of Medicine New Haven Connecticut USA.
Douglas M HildrewDivision of Otolaryngology - Head and Neck Surgery, Department of Surgery Yale University School of Medicine New Haven Connecticut USA.ORCID https://orcid.org/0000-0003-3310-479X
Yale University · USUniversity of Connecticut · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
NCATS NIH HHS UL1 TR001863
6 · The paper itself

Abstract

objectivesEndocannabinoid pathways have been proposed to affect the underlying pathophysiology of tinnitus. The aim of this study is to evaluate the scope and findings of existing literature on the relationship between

methodsWe conducted a review of animal, clinical and survey studies investigating the relationship between the use of

resultsAnimal studies revealed that cannabinoid receptor expression in the cochlear nucleus varied with tinnitus symptomatology and the use of cannabinoid agents either increased or had no effect on tinnitus-related behavior. Survey studies yielded conflicting results between

conclusionWhile animal studies have revealed that cannabinoid receptors likely have a role in modulating auditory signaling, there is no compelling data either from animal or human studies for the use of cannabinoids to alleviate tinnitus. Further research is necessary to elucidate their precise role to guide development of therapeutic interventions. LEVEL OF EVIDENCE: NA.

Indexed as

cannabinoid receptorscannabiscochlear nucleusendocannabinoidhearing lossmarijuanaotolaryngologyTHCtinnitus

Identifiers

PMID33364406
PMCPMC7752070
OpenAlexW3095578973

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.