Evidence map›Paper›PMID 33364394›Full record

ArticleLaryngoscope investigative otolaryngology2020

Risk factors of post-tonsillectomy hemorrhage in adults.

Yoshiaki Inuzuka, Kunio Mizutari, Daisuke Kamide, Michiya Sato, Akihiro Shiotani

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Laryngoscope investigative otolaryngology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05206799 (A Multi-centre Clinical Study of Hemorrhage Rate After Coblation Tonsillectomy in Children), which is not on this map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05206799 unknown statusnot on this mapstarted 2022, after this paper: background citation

A Multi-centre Clinical Study of Hemorrhage Rate After Coblation Tonsillectomy in Children

TypeobservationalSponsorShanghai Children's HospitalRan2022 to 2024Enrolled25,000ConditionsTonsillectomy, Child, Postoperative Hemorrhage
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.

  1. Tie or do not tie: comparing knot tying hemostasis in tonsillectomy with other methods of hemostasis. A systematic review and meta-analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
    Pooled it
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  13. Effect of Body Mass Index on Post Tonsillectomy Hemorrhages.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2023
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  14. Article
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  16. Post-tonsillectomy Hemorrhage: A Seven-year Retrospective Study.Iranian journal of otorhinolaryngology · 2021
    Article
  17. Risk factors of post-tonsillectomy hemorrhage in adults.Laryngoscope investigative otolaryngology · 2020
    Article
  18. Ninety-Day Emergency Department Rebound Following Adult Tonsillectomy: A Retrospective Cohort Study.Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Yoshiaki InuzukaDepartment of Otolaryngology-Head and Neck Surgery National Defense Medical College Tokorozawa Japan.
Kunio MizutariDepartment of Otolaryngology-Head and Neck Surgery National Defense Medical College Tokorozawa Japan.ORCID https://orcid.org/0000-0002-0340-8293
Daisuke KamideDepartment of Otolaryngology-Head and Neck Surgery Self-Defense Forces Central Hospital Setagaya-ku Japan.
Michiya SatoDepartment of Otolaryngology-Head and Neck Surgery Self-Defense Forces Central Hospital Setagaya-ku Japan.
Akihiro ShiotaniDepartment of Otolaryngology-Head and Neck Surgery National Defense Medical College Tokorozawa Japan.
National Defense Medical College · JPSelf-Defense Forces Central Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTonsillectomy is an essential surgery and is conducted on both children and adults. However, the risk factors of post-tonsillectomy hemorrhage for adult patients remain unclear. In this study, we analyzed post-tonsillectomy hemorrhage in adult patients.

methodsWe retrospectively analyzed 325 adult patients who underwent a tonsillectomy between 2014 and 2018 in our facilities.

resultsThe average age of this study's population was 31.7 ± 10.5 years (range: 19-70 years), and 250 (76.9%) patients were male. Overall, post-tonsillectomy hemorrhage occurred in 71 (21.8%) patients and 5 (1.5%) patients required a second surgery for hemostasis. Post-tonsillectomy hemorrhage often occurred on postoperative day zero or six. Using multiple logistic regression analysis, current smoking status (odds ratio 3.491; 95% confidence interval 1.813-6.723), male sex (odds ratio 3.924; 95% confidence interval 1.548-9.944), and perioperative non-steroidal anti-inflammatory drug administration (odds ratio 7.930; 95% confidence interval 1.004-62.64) were revealed as overall post-tonsillectomy hemorrhage risk factors. To analyze the hemorrhage period after tonsillectomy, we categorized the post-tonsillectomy hemorrhage patients into the primary (bleeding within postoperative day one) and secondary hemorrhage (bleeding on or after postoperative day two) groups. The current smoking status and older age were risk factors for primary hemorrhage and the current smoking status and sex (male) were risk factors for secondary hemorrhage.

conclusionsIn this study, smoking status, sex, and perioperative non-steroidal anti-inflammatory drug administration were the clinical risk factors for adult post-tonsillectomy hemorrhage. Thus, smoking cessation is, at least, mandatory for patients who receive tonsillectomy to avoid post-tonsillectomy hemorrhage. LEVEL OF EVIDENCE: 4.

Indexed as

adultadult tonsillectomypostoperative hemorrhagesmoking

Identifiers

PMID33364394
PMCPMC7752073
OpenAlexW3104503703

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.