Evidence map›Paper›PMID 33364259›Full record

ArticleEuropean journal of radiology open2021

MRI-based 3D models of the hip joint enables radiation-free computer-assisted planning of periacetabular osteotomy for treatment of hip dysplasia using deep learning for automatic segmentation.

Guodong Zeng, Florian Schmaranzer, Celia Degonda, Nicolas Gerber, Kate Gerber, Moritz Tannast, Jürgen Burger, Klaus A Siebenrock, Guoyan Zheng, Till D Lerch

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in European journal of radiology open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07581717 (Computer-Assisted Comparative Analysis of Acetabular Volume and Surface Morphology in Pediatric Acetabular Osteotomies), which is not on this map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07581717 recruitingnot on this mapstarted 2026, after this paper: background citation

Computer-Assisted Comparative Analysis of Acetabular Volume and Surface Morphology in Pediatric Acetabular Osteotomies (Salter, Dega, San Diego, and Pemberton)

TypeobservationalSponsorIstanbul UniversityRan2026 to 2026Enrolled12ConditionsDevelopmental Dysplasia of the Hip (DDH), Developmental Dysplasia of the Hip, Acetabular DysplasiaArmsSalter osteotomy, Dega osteotomy, San Diego osteotomy, Pemberton osteotomy
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
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  9. 3D Printing Technology in Pediatric Orthopedics: a Primer for the Clinician.Current reviews in musculoskeletal medicine · 2023
    Review
  10. Article
  11. Review
  12. Article
  13. Efficient cascaded V-net optimization for lower extremity CT segmentation validated using bone morphology assessment.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2022
    Article
  14. Article
  15. Article
  16. Review
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  19. Article
  20. Real-world analysis of artificial intelligence in musculoskeletal trauma.Journal of clinical orthopaedics and trauma · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Guodong ZengSitem Center for Translational Medicine and Biomedical Entrepreneurship, University of Bern, Switzerland.
Florian SchmaranzerDepartment of Orthopedic Surgery, Inselspital, University of Bern, Bern, Switzerland.
Celia DegondaDepartment of Orthopedic Surgery, Inselspital, University of Bern, Bern, Switzerland.
Nicolas GerberSitem Center for Translational Medicine and Biomedical Entrepreneurship, University of Bern, Switzerland.
Kate GerberSitem Center for Translational Medicine and Biomedical Entrepreneurship, University of Bern, Switzerland.
Moritz TannastDepartment of Orthopedic Surgery, Inselspital, University of Bern, Bern, Switzerland.
Jürgen BurgerSitem Center for Translational Medicine and Biomedical Entrepreneurship, University of Bern, Switzerland.
Klaus A SiebenrockDepartment of Orthopedic Surgery, Inselspital, University of Bern, Bern, Switzerland.
Guoyan ZhengInstitute for Medical Robotics, School of Biomedical Engineering, Shanghai Jiao Tong University, China.
Till D LerchDepartment of Orthopedic Surgery, Inselspital, University of Bern, Bern, Switzerland.
University of Bern · CHShanghai Jiao Tong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionBoth Hip Dysplasia(DDH) and Femoro-acetabular-Impingement(FAI) are complex three-dimensional hip pathologies causing hip pain and osteoarthritis in young patients. 3D-MRI-based models were used for radiation-free computer-assisted surgical planning. Automatic segmentation of MRI-based 3D-models are preferred because manual segmentation is time-consuming.To investigate(1) the difference and(2) the correlation for femoral head coverage(FHC) between automatic MR-based and manual CT-based 3D-models and (3) feasibility of preoperative planning in symptomatic patients with hip diseases.

methodsWe performed an IRB-approved comparative, retrospective study of 31 hips(26 symptomatic patients with hip dysplasia or FAI). 3D MRI sequences and CT scans of the hip were acquired. Preoperative MRI included axial-oblique T1 VIBE sequence(0.8 mm

results(1)The difference between automatic and manual segmentation of MRI-based 3D hip joint models was below 1 mm(proximal femur 0.2 ± 0.1 mm and acetabulum 0.3 ± 0.5 mm). Dice coefficients of the proximal femur and the acetabulum were 98 % and 97 %, respectively. (2)The correlation for total FHC was excellent and significant(r = 0.975, p < 0.001) between automatic MRI-based and manual CT-based 3D-models. Correlation for total FHC (r = 0.979, p < 0.001) between automatic and manual MR-based 3D models was excellent.(3)Preoperative planning and simulation of periacetabular osteotomy was feasible in all patients(100 %) with hip dysplasia or acetabular retroversion.

conclusionsAutomatic segmentation of MRI-based 3D-models using deep learning is as accurate as CT-based 3D-models for patients with hip diseases of childbearing age. This allows radiation-free and patient-specific preoperative simulation and surgical planning of periacetabular osteotomy for patients with DDH.

Indexed as

ASD, Average Surface DistanceAutomatic segmentationDDHDDH, developmental dysplasia of the hipDeep learningDOC, Dice Overlap CoefficientsFAI, Femoroacetabular ImpingementFHC, femoral head centerGPU, Graphics processing unitHip dysplasiaHip jointMachine learningMagnetic resonance imagingMRIROM, range of motion

Identifiers

PMID33364259
PMCPMC7753932
OpenAlexW3117186051

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.